Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 3/20 | 0.45 |
| ▸ | P2RX7 | Q99572 | 11/20 | 0.43 |
| ▸ | CACNA1S | Q13698 | 5/20 | 0.39 |
| ▸ | TTR | P02766 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27883829 | 0.81 | NOTUM (0.47) | NOTUMCACNA1STTR | |
| SCHEMBL27825463 | 0.81 | AADAT (0.44) | NOTUMP2RX7 | |
| SCHEMBL27825543 | 0.74 | AGTR2 (0.46) | — | |
| SCHEMBL9812500 | 0.73 | ACE (0.53) | — | |
| SCHEMBL9812508 | 0.73 | ACE (0.53) | — | |
| SCHEMBL27844514 | 0.73 | AGTR2 (0.47) | — | |
| Hydrochloric Acid SCHEMBL9740832 | 0.72 | ACE (0.52) | — | |
| SCHEMBL2428200 | 0.69 | NOTUM (0.55) | NOTUMCACNA1STTR | |
| SCHEMBL19436082 | 0.69 | CASP1 (0.35) | — | |
| SCHEMBL27825441 | 0.68 | AGTR2 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102239165-A | Inhibitors of diacylglycerol acyltransferase | VIA PHARMACEUTICALS INC | 2011-11-09 | — | — | CN | disclosed |