Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 4/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 7/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 2/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | HTR3A | P46098 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | HTR7 | P34969 | 1/20 | 0.35 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.34 |
| ▸ | HTR3B | O95264 | 1/20 | 0.34 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27951857 | 0.85 | KCNN4 (0.35) | CYP1A2CYP2C19CYP3A4 | |
| SCHEMBL27831055 | 0.81 | KMT2A (0.39) | DRD2DRD3CYP2D6HTR3AHTR3B | |
| SCHEMBL27513879 | 0.76 | CHRM2 (0.47) | ADRB1CYP1A2CYP2D6HTR1ASIGMAR1 | |
| SCHEMBL27831059 | 0.75 | NPSR1 (0.40) | ADRB1HTR7 | |
| SCHEMBL7769823 | 0.74 | KCNN4 (0.48) | ADRB1RXFP1DRD2DRD3SLC6A2 | |
| SCHEMBL15587141 | 0.69 | KCNN4 (0.46) | ADRB1RXFP1DRD2DRD3SLC6A2 | |
| SCHEMBL27546772 | 0.68 | KCNN4 (0.45) | ADRB1DRD2DRD3SLC6A2SLC6A4 | |
| Methylpiperazine SCHEMBL11763811 | 0.66 | RXFP1 (0.44) | ADRB1RXFP1DRD2DRD3SLC6A2 | |
| SCHEMBL5139721 | 0.66 | OPRD1 (0.49) | ADRB1CYP2D6HTR1ASIGMAR1HTR3A | |
| SCHEMBL2490789 | 0.66 | ALDH1A1 (0.41) | ADRB1SLC6A2SLC6A4SLC6A3CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102093319-B | 3-aryl-4-(2-glycosyl/amino ethyoxyl)-2(5H)-furanone compound, preparation method thereof and application thereof | UNIV JISHOU | 2013-01-23 | — | — | CN | disclosed |
| CN-102093319-A | 3-aryl-4-(2-glycosyl/amino ethyoxyl)-2(5H)-furanone compound, preparation method thereof and application thereof | UNIV JISHOU | 2011-06-15 | — | — | CN | disclosed |