Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGB1 | P09429 | 1/20 | 0.49 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.45 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.45 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.41 |
| ▸ | IAPP | P10997 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | HMGCR | P04035 | 1/20 | 0.35 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | SHBG | P04278 | 1/20 | 0.35 |
| ▸ | PNMT | P11086 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27420704 | 0.83 | L3MBTL1 (0.41) | HMGB1HSP90AB1MAPTKMT2APDK2 | |
| SCHEMBL16585595 | 0.83 | HMGB1 (0.53) | HMGB1GABRA1GABRB2MEN1MAPT | |
| SCHEMBL27753882 | 0.82 | GABRA1 (0.41) | HMGB1GABRA1GABRB2HSP90AB1MAPT | |
| SCHEMBL27733489 | 0.82 | ABCB11 (0.38) | HMGB1GABRA1GABRB2HSP90AB1PDK2 | |
| SCHEMBL27753896 | 0.82 | PNMT (0.47) | HMGB1GABRA1GABRB2HSP90AB1MAPT | |
| SCHEMBL14588767 | 0.82 | HMGB1 (0.49) | HMGB1GABRA1GABRB2HSP90AB1IAPP | |
| SCHEMBL14645911 | 0.81 | HMGB1 (0.55) | HMGB1GABRA1GABRB2IAPPKMT2A | |
| SCHEMBL27709094 | 0.81 | HMGB1 (0.37) | HMGB1GABRA1GABRB2HSP90AB1IAPP | |
| SCHEMBL27499175 | 0.81 | GABRA1 (0.44) | HMGB1GABRA1GABRB2HSP90AB1IAPP | |
| SCHEMBL11651879 | 0.79 | KDM4E (0.47) | GABRA1GABRB2HSP90AB1MEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102149687-B | Novel imidazolidine compounds as androgen receptor modulators | GALAPAGOS NV | 2014-08-13 | — | — | CN | disclosed |
| CN-102149687-A | Novel imidazolidine compounds as androgen receptor modulators | GALAPAGOS NV | 2011-08-10 | — | — | CN | disclosed |