Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | FLT3 | P36888 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 2/20 | 0.42 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | TTR | P02766 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27703407 | 0.86 | LMNA (0.44) | LMNAKDM4ECYP3A4FLT3ACHE | |
| SCHEMBL16857133 | 0.83 | HTR2A (0.43) | LMNAKDM4ECYP3A4FLT3ACHE | |
| SCHEMBL1846352 | 0.83 | LMNA (0.44) | LMNAKDM4ECYP3A4FLT3ACHE | |
| SCHEMBL27839938 | 0.80 | LMNA (0.42) | LMNAKDM4ECYP3A4FLT3ACHE | |
| SCHEMBL473532 | 0.80 | LMNA (0.52) | LMNAKDM4ECYP3A4FLT3ACHE | |
| SCHEMBL27593853 | 0.79 | LMNA (0.47) | LMNAKDM4ECYP3A4FLT3ACHE | |
| SCHEMBL772819 | 0.78 | ADRA1A (0.50) | TDP1 | |
| SCHEMBL28192543 | 0.77 | ACHE (0.51) | LMNAKDM4ECYP3A4FLT3ACHE | |
| SCHEMBL12578546 | 0.77 | MCL1 (0.46) | KDM4EALDH1A1MAPTPOLBPKM | |
| SCHEMBL27616069 | 0.77 | LMNA (0.42) | LMNAKDM4ECYP3A4FLT3ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102137848-A | 2,4-diaminopyrimidine compound | ASTELLAS PHARMA INC | 2011-07-27 | — | — | CN | disclosed |