Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.46 |
| ▸ | GLA | P06280 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | FLT3 | P36888 | 1/20 | 0.44 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | TTR | P02766 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22596400 | 0.82 | ACHE (0.51) | ACHELMNAKDM4EGLAGAA | |
| SCHEMBL27642118 | 0.81 | LMNA (0.44) | ACHELMNAKDM4EGLAGAA | |
| SCHEMBL27814169 | 0.81 | LMNA (0.44) | ACHELMNAKDM4EGLAGAA | |
| SCHEMBL27703407 | 0.81 | LMNA (0.44) | ACHELMNAKDM4EGLAGAA | |
| SCHEMBL14700558 | 0.79 | ACHE (0.49) | ACHELMNAKDM4EGLAGAA | |
| SCHEMBL28023568 | 0.79 | ACHE (0.49) | ACHELMNAKDM4EGLAGAA | |
| SCHEMBL862851 | 0.79 | ACHE (0.65) | ACHELMNAKDM4EGLAGAA | |
| SCHEMBL2600214 | 0.78 | ACHE (0.54) | ACHELMNAKDM4EGLAGAA | |
| SCHEMBL9847986 | 0.78 | THRB (0.46) | ACHELMNAKDM4EALDH1A1CYP3A4 | |
| SCHEMBL9847992 | 0.78 | THRB (0.46) | ACHELMNAKDM4EALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107522634-A | Biaryl ureas carboxylic acid derivates or its salt and its production and use | 复旦大学 | 2017-12-29 | — | — | CN | disclosed |