Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11064623 | 0.77 | TGFBR1 (0.35) | TGFBR1 | |
| SCHEMBL26390721 | 0.74 | TGFBR1 (0.36) | TGFBR1 | |
| Hydrochloric Acid SCHEMBL7109661 | 0.72 | TGFBR1 (0.35) | TGFBR1 | |
| Hydrochloric Acid SCHEMBL717635 | 0.72 | THRB (0.33) | TGFBR1 | |
| SCHEMBL9451788 | 0.69 | TGFBR1 (0.33) | TGFBR1 | |
| Hydrochloric Acid SCHEMBL2734343 | 0.69 | TGFBR1 (0.31) | TGFBR1 | |
| Hydrochloric Acid SCHEMBL201995 | 0.69 | THRB (0.32) | TGFBR1 | |
| Iodide SCHEMBL27449413 | 0.68 | TGFBR1 (0.32) | TGFBR1 | |
| SCHEMBL27631766 | 0.67 | TGFBR1 (0.34) | TGFBR1 | |
| SCHEMBL809315 | 0.67 | TGFBR1 (0.32) | TGFBR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102186892-A | Use of vinyl phosphonic acid for producing biodegradable mixed polymers and the use thereof for exploring and extracting petroleum and natural gas | CLARIANT INT LTD | 2011-09-14 | — | — | CN | disclosed |