Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9451788 | 0.98 | TGFBR1 (0.33) | THRBTGFBR1KDM4EALDH1A1BBOX1 | |
| Iodide SCHEMBL27449413 | 0.96 | TGFBR1 (0.32) | TGFBR1KDM4EALDH1A1BBOX1 | |
| Hydrochloric Acid SCHEMBL201995 | 0.85 | THRB (0.32) | THRBTGFBR1KDM4EALDH1A1 | |
| SCHEMBL809315 | 0.82 | TGFBR1 (0.32) | TGFBR1KDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL11064623 | 0.81 | TGFBR1 (0.35) | THRBTGFBR1KDM4EALDH1A1 | |
| Bromide SCHEMBL4456365 | 0.81 | DNM1 (0.32) | TGFBR1KDM4EALDH1A1 | |
| Water SCHEMBL7715787 | 0.81 | TGFBR1 (0.31) | TGFBR1KDM4EALDH1A1 | |
| SCHEMBL26390721 | 0.79 | TGFBR1 (0.36) | TGFBR1KDM4EALDH1A1 | |
| SCHEMBL3770023 | 0.78 | BBOX1 (0.37) | TGFBR1KDM4EALDH1A1BBOX1 | |
| Hydrochloric Acid SCHEMBL10949727 | 0.78 | TGFBR1 (0.33) | TGFBR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111909069-B | Degradable quaternary ammonium salt compound and preparation method and application thereof | 安徽启威生物科技有限公司 | 2022-04-19 | — | — | CN | claimed |
| US-11795255-B2 | Method for producing paper or cardboard | SOLENIS TECHNOLOGIES, L.P. (US) | 2023-10-24 | — | — | US | disclosed |
| CN-111909069-B | Degradable quaternary ammonium salt compound and preparation method and application thereof | 安徽启威生物科技有限公司 | 2022-04-19 | — | — | CN | disclosed |
| US-20220033555-A1 | METHOD FOR PRODUCING PAPER OR CARDBOARD | SOLENIS TECHNOLOGIES CAYMAN, L.P. (KY) | 2022-02-03 | — | — | US | disclosed |
| EP-3850020-A1 | METHOD FOR PRODUCING PAPER OR CARDBOARD | Solenis Technologies Cayman, L.P. (KY) | 2021-07-21 | — | — | EP | disclosed |
| CN-109439308-B | Weighted fracturing fluid of crosslinked glacial acetic acid and preparation method and application thereof | 中国石油天然气股份有限公司 | 2021-01-01 | — | — | CN | disclosed |
| CN-111909069-A | Degradable quaternary ammonium salt compound and preparation method and application thereof | 安徽启威生物科技有限公司 | 2020-11-10 | — | — | CN | disclosed |
| WO-2020053379-A1 | METHOD FOR PRODUCING PAPER OR CARDBOARD | SOLENIS TECHNOLOGIES CAYMAN, L.P. (KY) | 2020-03-19 | — | — | WO | disclosed |
| US-9579608-B2 | Composite membranes and methods of preparation thereof | GLOBALFOUNDRIES INC. (KY) | 2017-02-28 | — | — | US | disclosed |
| US-9352286-B2 | Composite filtration membranes and methods of preparation thereof | GLOBALFOUNDRIES INC. (KY) | 2016-05-31 | — | — | US | disclosed |
| US-20150202575-A1 | COMPOSITE MEMBRANES AND METHODS OF PREPARATION THEREOF | GLOBALFOUNDRIES U.S. INC. | 2015-07-23 | — | — | US | disclosed |
| US-9022227-B2 | Composite membranes and methods of preparation thereof | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2015-05-05 | — | — | US | disclosed |
| US-20140217014-A1 | COMPOSITE FILTRATION MEMBRANES AND METHODS OF PREPARATION THEREOF | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2014-08-07 | — | — | US | disclosed |
| US-8709536-B2 | Composite filtration membranes and methods of preparation thereof | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2014-04-29 | — | — | US | disclosed |
| US-20120241373-A1 | COMPOSITE MEMBRANES AND METHODS OF PREPARATION THEREOF | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2012-09-27 | — | — | US | disclosed |
| US-20120048799-A1 | COMPOSITE FILTRATION MEMBRANES AND METHODS OF PREPARATION THEREOF | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2012-03-01 | — | — | US | disclosed |
| EP-0415055-B1 | Water-soluble pressure-sensitive skin adhesive | ROEHM GMBH (DE) | 1994-12-14 | — | — | EP | disclosed |
| US-5250586-A | Dispersing particles in oil immiscible with polymer, then converting first dispersion to a second dispersion, the second having a lower content of surfactant than the first | SCANLEY CLYDE S (US) | 1993-10-05 | — | — | US | disclosed |
| US-5155156-A | Mixed with oil; flocculants for papermaking, oil recovery, sewage treatment | SCANLEY CLYDE S (US) | 1992-10-13 | — | — | US | disclosed |