Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.40 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.40 |
| ▸ | LOX | P28300 | 1/20 | 0.39 |
| ▸ | LOXL3 | P58215 | 1/20 | 0.39 |
| ▸ | LOXL4 | Q96JB6 | 1/20 | 0.39 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | GSK3A | P49840 | 2/20 | 0.35 |
| ▸ | GSK3B | P49841 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | FPR1 | P21462 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14446344 | 0.79 | LOX (0.43) | LMNAPTGS1ABCB11LOXLOXL3 | |
| SCHEMBL13415787 | 0.76 | LMNA (0.45) | LMNAPTGS1ABCB11LOXLOXL3 | |
| SCHEMBL9616703 | 0.76 | LOX (0.41) | LMNAPTGS1ABCB11LOXLOXL3 | |
| SCHEMBL9616973 | 0.73 | LOX (0.39) | LMNAPTGS1ABCB11LOXLOXL3 | |
| SCHEMBL19829483 | 0.73 | LOX (0.39) | LMNAPTGS1ABCB11LOXLOXL3 | |
| SCHEMBL20878207 | 0.70 | LMNA (0.43) | LMNAPTGS1ABCB11MAOASMN1; SMN2 | |
| SCHEMBL8217266 | 0.70 | LOX (0.36) | LMNAPTGS1ABCB11LOXLOXL3 | |
| SCHEMBL5193549 | 0.69 | LMNA (0.47) | LMNAPTGS1ABCB11MAOAGSK3A | |
| SCHEMBL13963799 | 0.68 | ALDH1A1 (0.40) | LMNAPTGS1ABCB11LOXLOXL3 | |
| SCHEMBL30834844 | 0.68 | POLB (0.35) | LMNAPTGS1ABCB11LOXLOXL3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010046256-A2 | METHOD FOR CONCEALING GRAY HAIRS | HENKEL AG & CO. KGAA (DE) | 2010-04-29 | — | — | WO | disclosed |