Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOX | P28300 | 1/20 | 0.39 |
| ▸ | LOXL3 | P58215 | 1/20 | 0.39 |
| ▸ | LOXL4 | Q96JB6 | 1/20 | 0.39 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 4/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.36 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.36 |
| ▸ | GSK3A | P49840 | 2/20 | 0.35 |
| ▸ | GSK3B | P49841 | 2/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | FPR1 | P21462 | 1/20 | 0.34 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14446344 | 0.79 | LOX (0.43) | LOXLOXL3LOXL4LOXL2MAOA | |
| SCHEMBL13415787 | 0.76 | LMNA (0.45) | LOXLOXL3LOXL4LOXL2MAOA | |
| SCHEMBL9616703 | 0.76 | LOX (0.41) | LOXLOXL3LOXL4LOXL2MAOA | |
| SCHEMBL9616973 | 0.73 | LOX (0.39) | LOXLOXL3LOXL4LOXL2MAOA | |
| SCHEMBL2784650 | 0.73 | LMNA (0.40) | LOXLOXL3LOXL4LOXL2MAOA | |
| SCHEMBL18015895 | 0.72 | LMNA (0.36) | LOXLOXL3LOXL4LOXL2MAOA | |
| SCHEMBL13963799 | 0.71 | ALDH1A1 (0.40) | LOXLOXL3LOXL4LOXL2MAOA | |
| SCHEMBL21694465 | 0.71 | LMNA (0.46) | LOXLOXL3LOXL4LOXL2MAOA | |
| SCHEMBL13669801 | 0.71 | MEN1 (0.50) | MAOALMNAALDH1A1TSHRKMT2A | |
| SCHEMBL15587183 | 0.70 | CYP2D6 (0.45) | MAOALMNACYP3A4CYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180028494-A1 | PHARMACEUTICAL COMPOSITION FOR TREATMENT OF INFLAMMATORY EAR DISEASES, METHOD FOR PRODUCING SAME AND METHOD FOR TREATMENT USING SAID COMPOSITION | LLC KONSORTSIUM-PIK (RU) | 2018-02-01 | — | — | US | disclosed |
| US-20180028494-A1 | PHARMACEUTICAL COMPOSITION FOR TREATMENT OF INFLAMMATORY EAR DISEASES, METHOD FOR PRODUCING SAME AND METHOD FOR TREATMENT USING SAID COMPOSITION | LLC KONSORTSIUM-PIK (RU) | 2018-02-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180028494-A1 | PHARMACEUTICAL COMPOSITION FOR TREATMENT OF INFLAMMATORY EAR DISEASES, METHOD FOR PRODUCING SAME AND METHOD FOR TREATMENT USING SAID COMPOSITION | P2RX5, P2RY4, P2RX3 | LOX 1172/4885LOXL3 843/4885LOXL4 670/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.