Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.47 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.43 |
| ▸ | FEN1 | P39748 | 1/20 | 0.43 |
| ▸ | ABL1 | P00519 | 1/20 | 0.40 |
| ▸ | PRKDC | P78527 | 1/20 | 0.40 |
| ▸ | ATR | Q13535 | 1/20 | 0.40 |
| ▸ | OXTR | P30559 | 1/20 | 0.40 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.40 |
| ▸ | USP7 | Q93009 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11679050 | 0.80 | IDO1 (0.50) | IDO1ALOX5APFEN1ABL1PRKDC | |
| SCHEMBL2030727 | 0.77 | FEN1 (0.66) | IDO1ALOX5APFEN1HSP90AA1HSP90AB1 | |
| SCHEMBL5934219 | 0.75 | ALPL (0.49) | IDO1ABL1PRKDCATRHPGD | |
| SCHEMBL15060604 | 0.73 | CYP1A2 (0.45) | IDO1ALOX5APFEN1ABL1OXTR | |
| SCHEMBL20068878 | 0.72 | USP7 (0.53) | IDO1ALOX5APFEN1ABL1USP7 | |
| SCHEMBL8136723 | 0.71 | HSD17B1 (0.52) | IDO1SMN1; SMN2MEN1KMT2ANPC1 | |
| SCHEMBL10900657 | 0.71 | IDO1 (0.48) | IDO1ALOX5APFEN1PRKDCATR | |
| SCHEMBL3948877 | 0.71 | IDO1 (0.48) | IDO1ALOX5APFEN1HPGDSMN1; SMN2 | |
| SCHEMBL18856143 | 0.69 | PABPC1 (0.37) | ALOX5APFEN1ATRHSP90AA1HSP90AB1 | |
| SCHEMBL13017168 | 0.69 | CYP1A2 (0.42) | IDO1ALOX5APFEN1OXTRAVPR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102209710-A | Pyrrolidines | PFIZER LTD | 2011-10-05 | — | — | CN | disclosed |