Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.52 |
| ▸ | HPGD | P15428 | 7/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.52 |
| ▸ | NPC1 | O15118 | 5/20 | 0.52 |
| ▸ | TP53 | P04637 | 5/20 | 0.52 |
| ▸ | RAB9A | P51151 | 5/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.52 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.52 |
| ▸ | RELA | Q04206 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | GLA | P06280 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.46 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.46 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27848407 | 0.81 | NPC1 (0.48) | ALDH1A1HPGDSMN1; SMN2HSD17B10KDM4E | |
| SCHEMBL27848320 | 0.81 | NPC1 (0.43) | ALDH1A1HPGDSMN1; SMN2HSD17B10KDM4E | |
| SCHEMBL2687461 | 0.75 | THRB (0.54) | ALDH1A1HPGDSMN1; SMN2HSD17B10KDM4E | |
| SCHEMBL27848324 | 0.74 | HPGD (0.44) | ALDH1A1HPGDSMN1; SMN2HSD17B10KDM4E | |
| SCHEMBL27848305 | 0.74 | NPC1 (0.44) | ALDH1A1HPGDSMN1; SMN2HSD17B10KDM4E | |
| SCHEMBL27865377 | 0.73 | PTPN2 (0.42) | ALDH1A1HPGDSMN1; SMN2HSD17B10KDM4E | |
| SCHEMBL592290 | 0.72 | ALDH1A1 (0.72) | ALDH1A1HPGDSMN1; SMN2HSD17B10KDM4E | |
| SCHEMBL27848485 | 0.72 | PTPN2 (0.40) | ALDH1A1HPGDSMN1; SMN2HSD17B10KDM4E | |
| SCHEMBL27848319 | 0.71 | MEN1 (0.48) | ALDH1A1HPGDSMN1; SMN2HSD17B10KDM4E | |
| SCHEMBL27865414 | 0.71 | MET (0.43) | ALDH1A1HPGDSMN1; SMN2HSD17B10KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102428080-A | Therapeutic or prophylactic agent for diseases in which neurotrophic factor activity participates | SUMITOMO CHEMICAL CO | 2012-04-25 | — | — | CN | disclosed |