Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.44 |
| ▸ | PTGER4 | P35408 | 7/20 | 0.43 |
| ▸ | NT5E | P21589 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.40 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.39 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.39 |
| ▸ | PRKD2 | Q9BZL6 | 1/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27851807 | 0.78 | MALT1 (0.49) | SIRT2NT5EHTTHTR1ADRD2 | |
| SCHEMBL27833746 | 0.77 | SIRT2 (0.46) | SIRT2NT5EHTTPTGDR2ALDH1A1 | |
| SCHEMBL27831429 | 0.69 | GRN (0.49) | SIRT2NT5EHTTHTR1ADRD2 | |
| SCHEMBL27831427 | 0.69 | MARS1 (0.53) | SIRT2NT5EHTTHTR1ADRD2 | |
| SCHEMBL27897837 | 0.68 | GHSR (0.42) | HTTPTGDR2ALDH1A1MAPTKMT2A | |
| SCHEMBL22897065 | 0.64 | CAPN1 (0.50) | — | |
| SCHEMBL13865187 | 0.63 | PTGER4 (0.67) | PTGER4ALDH1A1KMT2A | |
| SCHEMBL30336611 | 0.63 | MAPT (0.71) | HTTALDH1A1MAPTKMT2A | |
| SCHEMBL29156347 | 0.63 | F2RL3 (0.67) | PTGER4HTTALDH1A1MAPTKMT2A | |
| SCHEMBL474836 | 0.63 | ALDH1A1 (0.66) | ALDH1A1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102321074-B | Indole ring-substituted pyrazole hydrazide derivative and preparation method and application thereof | SHANDONG INST LIGHT INDUSTRY | 2013-04-10 | — | — | CN | claimed |
| CN-102321074-A | Indole ring-substituted pyrazole hydrazide derivative and preparation method and application thereof | SHANDONG INST LIGHT INDUSTRY | 2012-01-18 | — | — | CN | claimed |
| CN-102321074-B | Indole ring-substituted pyrazole hydrazide derivative and preparation method and application thereof | SHANDONG INST LIGHT INDUSTRY | 2013-04-10 | — | — | CN | disclosed |
| CN-102321074-A | Indole ring-substituted pyrazole hydrazide derivative and preparation method and application thereof | SHANDONG INST LIGHT INDUSTRY | 2012-01-18 | — | — | CN | disclosed |