Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | FPR1 | P21462 | 1/20 | 0.45 |
| ▸ | CPA1 | P15085 | 2/20 | 0.44 |
| ▸ | CPB1 | P15086 | 1/20 | 0.44 |
| ▸ | CPA3 | P15088 | 1/20 | 0.44 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | MMP1 | P03956 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
| ▸ | MMP9 | P14780 | 1/20 | 0.43 |
| ▸ | MMP8 | P22894 | 1/20 | 0.43 |
| ▸ | MMP13 | P45452 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.42 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.42 |
| ▸ | ELANE | P08246 | 1/20 | 0.42 |
| ▸ | PRTN3 | P24158 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27834323 | 0.83 | MMP12 (0.51) | CPA1CPB1CPA3CPB2CA2 | |
| SCHEMBL27852426 | 0.80 | CA2 (0.51) | HPGDALDH1A1CPA1CPB1CPA3 | |
| SCHEMBL12610359 | 0.78 | HPGD (0.51) | HPGDHSD17B10ALDH1A1FPR1CA1 | |
| SCHEMBL9574381 | 0.77 | HPGD (0.58) | HPGDHSD17B10ALDH1A1FPR1CA1 | |
| SCHEMBL6631110 | 0.76 | HPGD (0.54) | HPGDHSD17B10ALDH1A1FPR1CA1 | |
| SCHEMBL6631104 | 0.76 | HPGD (0.54) | HPGDHSD17B10ALDH1A1FPR1CA1 | |
| SCHEMBL14215519 | 0.75 | HPGD (0.56) | HPGDHSD17B10ALDH1A1FPR1CA1 | |
| SCHEMBL4430587 | 0.75 | ALPI (0.56) | HPGDHSD17B10ALDH1A1FPR1CA1 | |
| SCHEMBL498617 | 0.75 | ALDH1A1 (0.56) | HSD17B10ALDH1A1FPR1CA1CA2 | |
| SCHEMBL27852421 | 0.74 | HSD11B1 (0.47) | MMP2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104873982-A | PSMA binding ligand-linker conjugates and methods of use thereof | PURDUE RESEARCH FOUNDATION | 2015-09-02 | — | — | CN | disclosed |
| CN-102014956-B | PSMA binding ligand-linker conjugates and methods of use thereof | PURDUE RESEARCH FOUNDATION | 2015-06-03 | — | — | CN | disclosed |
| CN-102014956-A | PSMA binding ligand-linker conjugates and methods of use thereof | PURDUE RESEARCH FOUNDATION | 2011-04-13 | — | — | CN | disclosed |