Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.47 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.47 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | MMP12 | P39900 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27834323 | 0.90 | MMP12 (0.51) | CA2HDAC1HDAC8HDAC3HDAC4 | |
| SCHEMBL27852413 | 0.80 | HPGD (0.49) | CA2SMN1; SMN2MMP13CPA1HPGD | |
| SCHEMBL777369 | 0.77 | CA2 (0.71) | CA2HDAC1HDAC8HDAC3HDAC4 | |
| SCHEMBL7075239 | 0.77 | MMP2 (0.60) | CA2CPA1CPA3CPB2MMP1 | |
| SCHEMBL1376180 | 0.77 | CPA3 (0.59) | CA2HDAC1HDAC8HDAC3HDAC4 | |
| SCHEMBL18065715 | 0.72 | MMP12 (0.56) | HDAC1HDAC8HDAC3HDAC4HDAC7 | |
| SCHEMBL15686580 | 0.72 | CA2 (0.65) | CA2HDAC1HDAC8HDAC3HDAC4 | |
| SCHEMBL10899010 | 0.72 | CA2 (0.63) | CA2MAPTRXFP1ALDH1A1KMT2A | |
| SCHEMBL7078968 | 0.71 | MMP2 (0.60) | CA2MMP12MMP13CPA3CPB2 | |
| SCHEMBL8790146 | 0.71 | CA2 (0.62) | CA2HDAC1HDAC8HDAC3HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104873982-A | PSMA binding ligand-linker conjugates and methods of use thereof | PURDUE RESEARCH FOUNDATION | 2015-09-02 | — | — | CN | disclosed |
| CN-102014956-B | PSMA binding ligand-linker conjugates and methods of use thereof | PURDUE RESEARCH FOUNDATION | 2015-06-03 | — | — | CN | disclosed |
| CN-102014956-A | PSMA binding ligand-linker conjugates and methods of use thereof | PURDUE RESEARCH FOUNDATION | 2011-04-13 | — | — | CN | disclosed |