Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.52 |
| ▸ | NPC1 | O15118 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | MGLL | Q99685 | 13/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | MMP2 | P08253 | 1/20 | 0.49 |
| ▸ | MMP9 | P14780 | 1/20 | 0.49 |
| ▸ | MMP8 | P22894 | 1/20 | 0.49 |
| ▸ | MMP13 | P45452 | 1/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27452146 | 0.83 | NPC1 (0.55) | RAB9ANPC1MEN1KMT2AMGLL | |
| SCHEMBL7110254 | 0.83 | MGLL (0.72) | RAB9ANPC1MEN1KMT2AMGLL | |
| Hydrochloric Acid SCHEMBL7108023 | 0.81 | MGLL (0.70) | RAB9ANPC1MEN1KMT2AMGLL | |
| SCHEMBL27451640 | 0.80 | NPC1 (0.58) | RAB9ANPC1MEN1KMT2AMGLL | |
| SCHEMBL3947436 | 0.78 | DYRK1A (0.57) | RAB9ANPC1MGLLMAPTSMN1; SMN2 | |
| SCHEMBL7107229 | 0.77 | APP (0.63) | RAB9ANPC1MEN1KMT2AMGLL | |
| SCHEMBL2055238 | 0.77 | APP (0.67) | RAB9ANPC1MEN1KMT2AMAPT | |
| SCHEMBL16436146 | 0.77 | RAB9A (0.67) | RAB9ANPC1MEN1KMT2AMAPT | |
| SCHEMBL16238156 | 0.76 | NPC1 (0.61) | RAB9ANPC1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL4858014 | 0.74 | CSNK1D (0.69) | RAB9ANPC1MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102036972-A | Treatment of duchenne muscular dystrophy | SUMMIT CORP PLC | 2011-04-27 | — | — | CN | disclosed |