Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO1 | P15559 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10843251 | 0.89 | GAA (0.53) | KDM4ETSHRKMT2AALDH1A1MEN1 | |
| Hydrochloric Acid SCHEMBL27467648 | 0.86 | NQO1 (0.42) | NQO1KDM4ETSHRKMT2AALDH1A1 | |
| SCHEMBL13990320 | 0.85 | KDM4E (0.49) | NQO1KDM4ETSHRKMT2AALDH1A1 | |
| SCHEMBL278552 | 0.81 | LMNA (0.42) | KDM4EKMT2APTGDR2ALDH1A1MEN1 | |
| SCHEMBL6671333 | 0.81 | ALDH1A1 (0.47) | KDM4EKMT2APTGDR2ALDH1A1MEN1 | |
| SCHEMBL9885324 | 0.81 | KMT2A (0.47) | KDM4ETSHRKMT2APTGDR2ALDH1A1 | |
| SCHEMBL17688873 | 0.81 | NQO1 (0.48) | NQO1KDM4ETSHRKMT2AALDH1A1 | |
| SCHEMBL13334896 | 0.79 | NQO1 (0.46) | NQO1KDM4ETSHRKMT2AALDH1A1 | |
| SCHEMBL5083160 | 0.79 | ALDH1A1 (0.56) | NQO1KDM4EALDH1A1GAASMN1; SMN2 | |
| SCHEMBL13334863 | 0.79 | NQO1 (0.46) | NQO1TSHRKMT2AALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8133898-B2 | Renin inhibitors | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2012-03-13 | — | — | US | disclosed |
| US-8133898-B2 | Renin inhibitors | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2012-03-13 | — | — | US | disclosed |
| US-20100137310-A1 | RENIN INHIBITORS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-06-03 | — | — | US | disclosed |
| US-20080312435-A1 | Imine Compound | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2008-12-18 | — | — | US | disclosed |
| US-4631252-A | PHOTOGRAPHIC STABILIZERS | CIBA-GEIGY AG (CH) | 1986-12-23 | — | — | US | disclosed |
| US-4616082-A | PHOTOGRAPHIC STABILIZERS | CIBA-GEIGY AG (CH) | 1986-10-07 | — | — | US | disclosed |
| US-4549015-A | PHOTOHRAPHIC STABILIZERS | CIBA-GEIGY AG (CH) | 1985-10-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080312435-A1 | Imine Compound | CNR1, CNR2, HRH4 | NQO1 1815/4885KDM4E 3386/4885TSHR 181/4885 |
| US-20100137310-A1 | RENIN INHIBITORS | REN, ACE, PRSS3 | NQO1 174/4885KDM4E 3124/4885TSHR 2994/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.