Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | NAMPT | P43490 | 2/20 | 0.42 |
| ▸ | AGPAT2 | O15120 | 3/20 | 0.42 |
| ▸ | POLQ | O75417 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.41 |
| ▸ | ALPL | P05186 | 1/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.41 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.40 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.40 |
| ▸ | ATR | Q13535 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2785788 | 0.89 | KCNMA1 (0.51) | HTR2AHTR2CKCNMA1 | |
| SCHEMBL1825361 | 0.85 | KCNMA1 (0.52) | POLQRAB9AKCNMA1TAS1R3TAS1R1 | |
| SCHEMBL2784528 | 0.78 | ORAI1 (0.62) | LMNA | |
| SCHEMBL2784671 | 0.78 | FAAH (0.46) | NAMPTRAB9A | |
| SCHEMBL2784668 | 0.78 | PORCN (0.42) | — | |
| SCHEMBL2784233 | 0.78 | ORAI1 (0.58) | HTR2AHTR2CKCNMA1 | |
| SCHEMBL2786000 | 0.78 | FAAH (0.46) | NAMPTRAB9A | |
| SCHEMBL2785484 | 0.75 | IL2 (0.50) | HTR2CNAMPTAGPAT2 | |
| SCHEMBL2785920 | 0.75 | PDE10A (0.40) | RAB9A | |
| SCHEMBL2785271 | 0.74 | F11 (0.50) | LMNARAB9AKCNMA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1651232-B1 | COMPOUNDS FOR INFLAMMATION AND IMMUNE-RELATED USES | SYNTA PHARMACEUTICALS CORP (US) | 2010-12-22 | — | — | EP | claimed |