Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.34 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.34 |
| ▸ | MLYCD | O95822 | 1/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3674439 | 0.81 | MTNR1A (0.38) | PLA2G10PLA2G5EPHX1ALDH1A1KMT2A | |
| SCHEMBL8563016 | 0.79 | TSHR (0.48) | HRH3EPHX2ALDH1A1KMT2AMEN1 | |
| SCHEMBL27692814 | 0.79 | MTNR1A (0.39) | HRH3PLA2G10PLA2G5EPHX1ALDH1A1 | |
| SCHEMBL10982252 | 0.75 | CYP4F2 (0.50) | HRH3ALDH1A1KMT2ANR1H2MTNR1A | |
| Cyclohexane SCHEMBL27625968 | 0.72 | LMNA (0.44) | EPHX2EPHX1ALDH1A1STING1HDAC3 | |
| SCHEMBL644646 | 0.72 | TSHR (0.45) | EPHX2ALDH1A1STING1GAAHDAC3 | |
| SCHEMBL15355129 | 0.72 | MEN1 (0.50) | EPHX1ALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL8349429 | 0.69 | MEN1 (0.48) | ALDH1A1KMT2AMEN1MAPTHPGD | |
| SCHEMBL26667580 | 0.69 | HPGD (0.46) | ALDH1A1KMT2AMEN1MAPTHPGD | |
| SCHEMBL29059892 | 0.69 | FFAR1 (0.48) | HRH3NR1H2HDAC1HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102365273-A | Thiadiazole and oxadiazole derivatives, preparation thereof, and therapeutic use thereof | SANOFI AVENTIS | 2012-02-29 | — | — | CN | disclosed |