Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27516449 | 0.78 | MTNR1A (0.37) | — | |
| SCHEMBL28311081 | 0.77 | KDM4E (0.36) | ACHE | |
| SCHEMBL28311915 | 0.76 | ACHE (0.42) | ACHE | |
| SCHEMBL28875499 | 0.72 | ACHE (0.41) | ACHE | |
| SCHEMBL6578816 | 0.68 | PDK1 (0.47) | ACHE | |
| SCHEMBL27858113 | 0.67 | ACHE (0.48) | ACHE | |
| SCHEMBL8187421 | 0.67 | ACHE (0.42) | ACHE | |
| SCHEMBL28043420 | 0.67 | DRD2 (0.49) | — | |
| SCHEMBL12629125 | 0.66 | ACHE (0.43) | ACHE | |
| SCHEMBL12081005 | 0.65 | BRD4 (0.50) | ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102482234-B | Nitrogen-containing compounds and pharmaceutical compositions thereof for the treatment of atrial fibrillation | OTSUKA PHARMACEUTICAL CO.,LTD. (JP) | 2016-04-13 | — | — | CN | disclosed |
| CN-102482234-A | Nitrogen-containing compounds and pharmaceutical compositions | OTSUKA PHARMA CO LTD | 2012-05-30 | — | — | CN | disclosed |