Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | FLT1 | P17948 | 2/20 | 0.37 |
| ▸ | FLT4 | P35916 | 2/20 | 0.37 |
| ▸ | KDR | P35968 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 3/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | METAP2 | P50579 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4897962 | 0.88 | ALDH1A1 (0.51) | ALDH1A1TSHRFLT1FLT4KDR | |
| SCHEMBL4899206 | 0.82 | LMNA (0.47) | ALDH1A1TSHRFLT1FLT4KDR | |
| SCHEMBL27949917 | 0.76 | GABRA1 (0.35) | TSHRGAAL3MBTL1 | |
| SCHEMBL7946185 | 0.71 | VCAM1 (0.38) | ALDH1A1FLT1FLT4KDRLMNA | |
| SCHEMBL631838 | 0.71 | TSHR (0.48) | ALDH1A1TSHRLMNAL3MBTL1KMT2A | |
| SCHEMBL20078748 | 0.71 | TDP1 (0.39) | ALDH1A1TSHRFLT1FLT4KDR | |
| SCHEMBL11046300 | 0.71 | ALDH1A1 (0.37) | ALDH1A1FLT1FLT4KDRCA2 | |
| SCHEMBL29541454 | 0.70 | ALDH1A1 (0.49) | ALDH1A1TSHRFLT1FLT4KDR | |
| SCHEMBL16908486 | 0.70 | CHRNA7 (0.47) | TSHRLMNAKDM4EL3MBTL1CA2 | |
| SCHEMBL27584947 | 0.69 | ESR1 (0.47) | CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102282131-A | Novel benzenesulfonamides as calcium channel blockers | — | 2011-12-14 | — | — | CN | disclosed |