SCHEMBL2786372

SCHEMBL2786372

[O-][S+](c1cccs1)c1cccs1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FBP1 P09467 1/20 0.38
CES2 O00748 1/20 0.35
CES1 P23141 1/20 0.35
TSHR P16473 1/20 0.35
HSD17B10 Q99714 1/20 0.35
NPC1 O15118 3/20 0.33
RAB9A P51151 3/20 0.33
DAO P14920 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
ALDH1A1 P00352 3/20 0.32
MEN1 O00255 2/20 0.32
KMT2A Q03164 2/20 0.32
ATM Q13315 1/20 0.32
TAAR1 Q96RJ0 1/20 0.32
KDM4E B2RXH2 1/20 0.32
MAPT P10636 1/20 0.32
HPGD P15428 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
LTA4H P09960 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1251856 0.89 MEN1 (0.32) DAOMEN1KMT2A
SCHEMBL12762162 0.79 FBP1 (0.39) FBP1CES2CES1TSHRHSD17B10
SCHEMBL711758 0.78
SCHEMBL763933 0.78
SCHEMBL1609001 0.78
SCHEMBL30006285 0.78 HTT (0.38) TSHRHSD17B10NPC1RAB9ASMN1; SMN2
SCHEMBL19292761 0.72 ALDH1A1 (0.33) FBP1HSD17B10NPC1RAB9ASMN1; SMN2
SCHEMBL8043864 0.72
SCHEMBL4761802 0.69 KMT2A (0.33) FBP1CES2CES1TSHRHSD17B10
SCHEMBL246867 0.69 KMT2A (0.33) FBP1CES2CES1TSHRHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110256400-A A kind of sulfoxide participation aryl is combined to the preparation method of polysubstituted ring 1,2- diketone 南京林业大学 2019-09-20 CN claimed
EP-2961756-A1 COMPLEX CATALYSTS BASED ON AMINO-PHOSPHINE LIGANDS FOR HYDROGENATION AND DEHYDROGENATION PROCESSES Goussev, Dmitri (CA) 2016-01-06 EP claimed
EP-2892879-A1 CATALYSTS BASED ON AMINO-SULFIDE LIGANDS FOR HYDROGENATION AND DEHYDROGENATION PROCESSES Goussev, Dmitri (CA) 2015-07-15 EP claimed
WO-2014139030-A1 COMPLEX CATALYSTS BASED ON AMINO-PHOSPHINE LIGANDS FOR HYDROGENATION AND DEHYDROGENATION PROCESSES GOUSSEV DMITRI (CA) 2014-09-18 WO claimed
EP-2744815-A1 HYDROGENATION AND DEHYDROGENATION CATALYST, AND METHODS OF MAKING AND USING THE SAME Goussev, Dmitri (CA) 2014-06-25 EP claimed
WO-2014036650-A1 CATALYSTS BASED ON AMINO-SULFIDE LIGANDS FOR HYDROGENATION AND DEHYDROGENATION PROCESSES GOUSSEV DMITRI (CA) 2014-03-13 WO claimed
WO-2013023307-A1 HYDROGENATION AND DEHYDROGENATION CATALYST, AND METHODS OF MAKING AND USING THE SAME GOUSSEV DMITRI (CA) 2013-02-21 WO claimed
US-5763460-A N-(piperidinyl-1-alkyl)-substituted cyclohexane carboxylic acid amides as 5-htia receptor antagonists JOHN WYETH & BROTHER LIMITED (US) 1998-06-09 US claimed
CN-110785170-B Treatment of adipocytes 梅里奥尔医药I公司 2023-03-28 CN disclosed
CN-110256400-B Preparation method for synthesizing polysubstituted ring 1, 2-diketone by participation of sulfoxide in arylation 南京林业大学 2021-08-24 CN disclosed
CN-110678458-A Substituted cyclyl-acetic acid derivatives for the treatment of metabolic disorders 武田药品工业株式会社 2020-01-10 CN disclosed
CN-110256400-A A kind of sulfoxide participation aryl is combined to the preparation method of polysubstituted ring 1,2- diketone 南京林业大学 2019-09-20 CN disclosed
EP-2218715-B1 PHOTOACID GENERATOR AND PHOTOREACTIVE COMPOSITION SUMITOMO SEIKA CHEMICALS (JP) 2017-06-28 EP disclosed
WO-2016039691-A1 CATALYSTS FOR MAKING CHIRAL HETEROCYCLIC SULFOXIDES NANYANG TECHNOLOGICAL UNIVERSITY (SG) 2016-03-17 WO disclosed
EP-0086775-A1 HETEROCYCLIC AMIDINO SUBSTITUTED UREAS AND THEIR PHARMACEUTICAL USES RORER INTERNATIONAL (OVERSEAS) INC. (US) 1983-08-31 EP disclosed
EP-0079377-A1 HETEROCYCLIC ALKYLENE AMIDINOUREAS RORER INTERNATIONAL (OVERSEAS) INC. (US) 1983-05-25 EP disclosed
EP-0078839-A1 HETEROCYCLIC AMIDINOUREAS RORER INTERNATIONAL (OVERSEAS) INC. (US) 1983-05-18 EP disclosed
WO-1983000627-A1 HETEROCYCLIC AMIDINO SUBSTITUTED UREAS AND THEIR PHARMACEUTICAL USES STUDT, WILLIAM, LYON 1983-03-03 WO disclosed
WO-1982004047-A1 HETEROCYCLIC AMIDINOUREAS RORER INT OVERSEAS (US) 1982-11-25 WO disclosed
WO-1982004048-A1 HETEROCYCLIC ALKYLENE AMIDINOUREAS RORER INT OVERSEAS (US) 1982-11-25 WO disclosed