⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2786372 | 0.78 | FBP1 (0.38) | — | |
| SCHEMBL12762162 | 0.75 | FBP1 (0.39) | — | |
| SCHEMBL763933 | 0.74 | — | — | |
| SCHEMBL1609001 | 0.74 | — | — | |
| SCHEMBL19292761 | 0.69 | ALDH1A1 (0.33) | — | |
| SCHEMBL8043864 | 0.69 | — | — | |
| SCHEMBL1251856 | 0.68 | MEN1 (0.32) | — | |
| SCHEMBL28498479 | 0.66 | LMNA (0.33) | — | |
| SCHEMBL4761802 | 0.65 | KMT2A (0.33) | — | |
| SCHEMBL246867 | 0.65 | KMT2A (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8124617-B2 | Imidazopyridine compounds | TAKEDA SAN DIEGO, INC. (US) | 2012-02-28 | — | — | US | disclosed |
| US-20100069431-A1 | IMIDAZOPYRIDINE COMPOUNDS | TAKEDA SAN DIEGO, INC. | 2010-03-18 | — | — | US | disclosed |
| EP-1940837-A2 | IMIDAZOPYRIDINE COMPOUNDS | Takeda Pharmaceutical Company Limited (JP) | 2008-07-09 | — | — | EP | disclosed |
| WO-2007028135-A2 | IMIDAZOPYRIDINE COMPOUNDS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-03-08 | — | — | WO | disclosed |