SCHEMBL2787269

SCHEMBL2787269

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nearest known ligand 0.49

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ GZMB P10144 4/20 0.49
▸ TASP1 Q9H6P5 1/20 0.40
▸ CASP1 P29466 3/20 0.38
▸ CASP3 P42574 2/20 0.38
▸ MEN1 O00255 1/20 0.36
▸ KMT2A Q03164 1/20 0.36
▸ SMN1; SMN2 Q16637 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15485396 0.83 TASP1 (0.49) GZMBTASP1
SCHEMBL3629732 0.82 MEN1 (0.42) GZMBMEN1KMT2ASMN1; SMN2
SCHEMBL12149992 0.82 ENPEP (0.42) —
SCHEMBL23924919 0.81 TASP1 (0.52) GZMBTASP1CASP1CASP3
SCHEMBL20257131 0.81 TASP1 (0.52) GZMBTASP1CASP1CASP3
SCHEMBL2381289 0.81 TASP1 (0.52) GZMBTASP1CASP1CASP3
SCHEMBL23133165 0.81 TASP1 (0.52) GZMBTASP1CASP1CASP3
SCHEMBL23132679 0.81 TASP1 (0.52) GZMBTASP1CASP1CASP3
SCHEMBL5746872 0.78 TASP1 (0.61) GZMBTASP1CASP1CASP3
SCHEMBL22860748 0.77 PSMB5 (0.44) MEN1KMT2ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100255120-A1 COMPOSITIONS FOR FORMING IMMOBILIZED BIOLOGICAL LAYERS FOR SENSING ABBOTT POINT OF CARE INC. 2010-10-07 — — US claimed
US-9441259-B2 Formation of immobilized biological layers for sensing ABBOTT POINT OF CARE INC. (US) 2016-09-13 — — US disclosed
EP-2225388-B1 COMPOSITIONS FOR FORMING IMMOBILIZED BIOLOGICAL LAYERS FOR SENSING ABBOTT POINT OF CARE INC (US) 2016-03-30 — — EP disclosed
US-20150275261-A1 FORMATION OF IMMOBILIZED BIOLOGICAL LAYERS FOR SENSING ABBOTT POINT OF CARE INC. (US) 2015-10-01 — — US disclosed
US-8986526-B2 Formation of immobilized biological layers for sensing ABBOTT POINT OF CARE INC. (US) 2015-03-24 — — US disclosed
EP-2235513-B1 FORMATION OF IMMOBILIZED BIOLOGICAL LAYERS FOR SENSING ABBOTT POINT OF CARE INC (US) 2014-05-07 — — EP disclosed
US-20130112558-A1 FORMATION OF IMMOBILIZED BIOLOGICAL LAYERS FOR SENSING ABBOTT POINT OF CARE INC. (US) 2013-05-09 — — US disclosed
US-8389042-B2 Formation of immobilized biological layers for sensing ABBOTT POINT OF CARE INC. (US) 2013-03-05 — — US disclosed
US-20120270756-A1 FORMATION OF IMMOBILIZED BIOLOGICAL LAYERS FOR SENSING ABBOTT POINT OF CARE INC. (US) 2012-10-25 — — US disclosed
US-8241697-B2 Formation of immobilized biological layers for sensing ABBOTT POINT OF CARE INC. (US) 2012-08-14 — — US disclosed
US-20100255120-A1 COMPOSITIONS FOR FORMING IMMOBILIZED BIOLOGICAL LAYERS FOR SENSING ABBOTT POINT OF CARE INC. 2010-10-07 — — US disclosed
EP-2235513-A1 FORMATION OF IMMOBILIZED BIOLOGICAL LAYERS FOR SENSING Abbott Point Of Care, Inc. (US) 2010-10-06 — — EP disclosed
WO-2009105145-A1 FORMATION OF IMMOBILIZED BIOLOGICAL LAYERS FOR SENSING I-STAT CORPORATION (US) 2009-08-27 — — WO disclosed
US-20090159442-A1 FORMATION OF IMMOBILIZED BIOLOGICAL LAYERS FOR SENSING ABBOTT POINT OF CARE INC. 2009-06-25 — — US disclosed
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