SCHEMBL15485396

SCHEMBL15485396

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nearest known ligand 0.49

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ TASP1 Q9H6P5 1/20 0.49
▸ GZMB P10144 3/20 0.44
▸ ENPEP Q07075 11/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20257131 0.88 TASP1 (0.52) TASP1GZMBENPEP
SCHEMBL2381289 0.88 TASP1 (0.52) TASP1GZMBENPEP
SCHEMBL23924919 0.88 TASP1 (0.52) TASP1GZMBENPEP
SCHEMBL23132679 0.88 TASP1 (0.52) TASP1GZMBENPEP
SCHEMBL23133165 0.88 TASP1 (0.52) TASP1GZMBENPEP
SCHEMBL15485472 0.86 ENPEP (0.39) TASP1ENPEP
SCHEMBL5746872 0.85 TASP1 (0.61) TASP1GZMBENPEP
SCHEMBL2787269 0.83 GZMB (0.49) TASP1GZMB
SCHEMBL20257263 0.80 TASP1 (0.53) TASP1GZMBENPEP
SCHEMBL20257260 0.80 TASP1 (0.53) TASP1GZMBENPEP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140056964-A1 GRANZYME B INHIBITOR COMPOSITIONS, METHODS AND USES FOR PROMOTING WOUND HEALING THE UNIVERSITY OF BRITISH COLUMBIA (CA) 2014-02-27 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140056964-A1 GRANZYME B INHIBITOR COMPOSITIONS, METHODS AND USES FOR PROMOTING WOUND HEALING GZMB, PRF1, SERPINB1 TASP1 3637/4885GZMB 1/4885ENPEP 319/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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