Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TASP1 | Q9H6P5 | 1/20 | 0.61 |
| ▸ | CASP1 | P29466 | 2/20 | 0.49 |
| ▸ | CASP3 | P42574 | 2/20 | 0.49 |
| ▸ | CASP4 | P49662 | 2/20 | 0.49 |
| ▸ | CASP5 | P51878 | 2/20 | 0.49 |
| ▸ | CASP9 | P55211 | 2/20 | 0.49 |
| ▸ | CASP6 | P55212 | 2/20 | 0.49 |
| ▸ | CASP8 | Q14790 | 2/20 | 0.49 |
| ▸ | CASP10 | Q92851 | 2/20 | 0.49 |
| ▸ | MAGI3 | Q5TCQ9 | 1/20 | 0.49 |
| ▸ | ENPEP | Q07075 | 5/20 | 0.43 |
| ▸ | CASP7 | P55210 | 1/20 | 0.42 |
| ▸ | GZMB | P10144 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7067113 | 0.93 | TASP1 (0.62) | TASP1CASP1CASP3CASP4CASP5 | |
| SCHEMBL23133165 | 0.93 | TASP1 (0.52) | TASP1CASP1CASP3CASP4CASP5 | |
| SCHEMBL2381289 | 0.93 | TASP1 (0.52) | TASP1CASP1CASP3CASP4CASP5 | |
| SCHEMBL23132679 | 0.93 | TASP1 (0.52) | TASP1CASP1CASP3CASP4CASP5 | |
| SCHEMBL20257131 | 0.93 | TASP1 (0.52) | TASP1CASP1CASP3CASP4CASP5 | |
| SCHEMBL23924919 | 0.93 | TASP1 (0.52) | TASP1CASP1CASP3CASP4CASP5 | |
| SCHEMBL20257263 | 0.85 | TASP1 (0.53) | TASP1CASP1CASP3CASP4CASP5 | |
| SCHEMBL20257260 | 0.85 | TASP1 (0.53) | TASP1CASP1CASP3CASP4CASP5 | |
| SCHEMBL15485396 | 0.85 | TASP1 (0.49) | TASP1ENPEPGZMB | |
| SCHEMBL23133164 | 0.85 | TASP1 (0.50) | TASP1CASP1CASP3CASP4CASP5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1517997-A4 | LUMINOGENIC PROTEASE SUBSTRATES | MOLECULAR DEVICES CORP (US) | 2006-11-15 | — | — | EP | disclosed |
| EP-1517997-A2 | LUMINOGENIC PROTEASE SUBSTRATES | MOLECULAR DEVICES CORPORATION (US) | 2005-03-30 | — | — | EP | disclosed |
| WO-2003099780-A2 | LUMINOGENIC PROTEASE SUBSTRATES | MOLECULAR DEVICES CORPORATION (US) | 2003-12-04 | — | — | WO | disclosed |