SCHEMBL20257131

SCHEMBL20257131

CC[C@H](C)[C@H](NC(C)=O)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@H](C(=O)N[C@H](C=O)CC(=O)O)[C@@H](C)O

nearest known ligand 0.52

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ TASP1 Q9H6P5 1/20 0.52
▸ ENPEP Q07075 5/20 0.47
▸ GZMB P10144 2/20 0.44
▸ CASP1 P29466 1/20 0.42
▸ CASP3 P42574 1/20 0.42
▸ CASP4 P49662 1/20 0.42
▸ CASP5 P51878 1/20 0.42
▸ CASP9 P55211 1/20 0.42
▸ CASP6 P55212 1/20 0.42
▸ CASP8 Q14790 1/20 0.42
▸ CASP10 Q92851 1/20 0.42
▸ MAGI3 Q5TCQ9 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23132679 1.00 TASP1 (0.52) TASP1ENPEPGZMBCASP1CASP3
SCHEMBL2381289 1.00 TASP1 (0.52) TASP1ENPEPGZMBCASP1CASP3
SCHEMBL23924919 1.00 TASP1 (0.52) TASP1ENPEPGZMBCASP1CASP3
SCHEMBL23133165 1.00 TASP1 (0.52) TASP1ENPEPGZMBCASP1CASP3
SCHEMBL5746872 0.93 TASP1 (0.61) TASP1ENPEPGZMBCASP1CASP3
SCHEMBL20257260 0.93 TASP1 (0.53) TASP1ENPEPGZMBCASP1CASP3
SCHEMBL20257263 0.93 TASP1 (0.53) TASP1ENPEPGZMBCASP1CASP3
SCHEMBL15485396 0.88 TASP1 (0.49) TASP1ENPEPGZMB
SCHEMBL23133164 0.87 TASP1 (0.50) TASP1ENPEPGZMBCASP1CASP3
SCHEMBL29729257 0.87 ENPEP (0.47) TASP1ENPEPCASP1CASP3CASP4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4709405-A2 FLUORESCEIN-LABELED NERVE TARGETING PEPTIDE FORMULATIONS AND RELATED METHODS Alume Biosciences, Inc. (US) 2026-03-18 — — EP disclosed
US-12533425-B2 Methods and systems using peptides for targeting and mapping human nerves in image guided surgery, diagnostics and therapeutic delivery ALUME BIOSCIENCES, INC. (US) 2026-01-27 — — US disclosed
US-20250146050-A1 STABILISATION OF BIOLOGICAL SAMPLES QIAGEN GMBH (DE) 2025-05-08 — — US disclosed
US-20250122555-A1 STABILISATION OF BIOLOGICAL SAMPLES QIAGEN GMBH (DE) 2025-04-17 — — US disclosed
US-12240816-B2 Deuterated compounds and uses thereof ALDEYRA THERAPEUTICS, INC. (US) 2025-03-04 — — US disclosed
EP-4493275-A1 METHODS AND COMPOSITIONS FOR IMPROVING IN VIVO SURVIVAL OF MIDBRAIN DOPAMINE NEURONS Memorial Sloan Kettering Cancer Center (US) 2025-01-22 — — EP disclosed
US-20250017979-A1 METHODS AND COMPOSITIONS FOR IMPROVING IN VIVO SURVIVAL OF MIDBRAIN DOPAMINE NEURONS MEMORIAL SLOAN-KETTERING CANCER CENTER (US) 2025-01-16 — — US disclosed
EP-4484952-A2 OPTIMIZED PEPTIDES FOR TARGETING HUMAN NERVES AND THEIR USE IN IMAGE GUIDED SURGERY, DIAGNOSTICS AND THERAPEUTIC DELIVERY The Regents of the University of California (US) 2025-01-01 — — EP disclosed
WO-2024233683-A2 FLUORESCEIN-LABELED NERVE TARGETING PEPTIDE FORMULATIONS AND RELATED METHODS ALUME BIOSCIENCES, INC. (US) 2024-11-14 — — WO disclosed
US-12139744-B2 Stabilisation of biological samples QIAGEN GMBH (DE) 2024-11-12 — — US disclosed
EP-4041311-A1 METHODS AND SYSTEMS USING PEPTIDES FOR TARGETING AND MAPPING HUMAN NERVES IN IMAGE GUIDED SURGERY, DIAGNOSTICS AND THERAPEUTIC DELIVERY Alume Biosciences, Inc. (US) 2022-08-17 — — EP disclosed
EP-4037714-A1 METHODS AND COMPOSITIONS FOR MODULATING MACROPHAGES POLARIZATION INSERM (Institut National de la Santé et de la Recherche Médicale) (FR) 2022-08-10 — — EP disclosed
WO-2022120177-A1 NERVE TARGETING PEPTIDES AND METHODS OF USE ALUME BIOSCIENCES, INC. (US) 2022-06-09 — — WO disclosed
US-11299515-B2 Optimized peptides for targeting human nerves and their use in image guided surgery, diagnostics and therapeutic THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2022-04-12 — — US disclosed
US-11246940-B2 Peptides whose uptake in cells is controllable THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2022-02-15 — — US disclosed
US-11052154-B2 Ras protein degradation inducing molecule and pharmaceutical composition TOKYO UNIVERSITY OF SCIENCE FOUNDATION (JP) 2021-07-06 — — US disclosed
US-11007269-B2 P53 degradation inducing molecule and pharmaceutical composition TOKYO UNIVERSITY OF SCIENCE FOUNDATION (JP) 2021-05-18 — — US disclosed
US-10976306-B2 Protein degradation inducing tag and usage thereof TOKYO UNIVERSITY OF SCIENCE FOUNDATION (JP) 2021-04-13 — — US disclosed
US-20190314508-A1 P53 DEGRADATION INDUCING MOLECULE AND PHARMACEUTICAL COMPOSITION TOKYO UNIVERSITY OF SCIENCE FOUNDATION (JP) 2019-10-17 — — US disclosed
US-20180164289-A1 PROTEIN DEGRADATION INDUCING TAG AND USAGE THEREOF TOKYO UNIVERSITY OF SCIENCE FOUNDATION (JP) 2018-06-14 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10976306-B2 Protein degradation inducing tag and usage thereof SENP8, SENP6, SENP7 TASP1 1024/4885ENPEP 318/4885GZMB 2908/4885
US-20190314508-A1 P53 DEGRADATION INDUCING MOLECULE AND PHARMACEUTICAL COMPOSITION TP53, TP53BP1, MDM2 TASP1 1006/4885ENPEP 566/4885GZMB 1427/4885
US-20250122555-A1 STABILISATION OF BIOLOGICAL SAMPLES RNASE1, RNASEH1, EWSR1 TASP1 4313/4885ENPEP 1297/4885GZMB 426/4885
US-11052154-B2 Ras protein degradation inducing molecule and pharmaceutical composition KRAS, G3BP1, NRAS TASP1 960/4885ENPEP 864/4885GZMB 2737/4885
US-20180164289-A1 PROTEIN DEGRADATION INDUCING TAG AND USAGE THEREOF SENP8, SENP6, SENP7 TASP1 1024/4885ENPEP 318/4885GZMB 2908/4885
US-12533425-B2 Methods and systems using peptides for targeting and mapping human nerves in image guided surgery, diagnostics and therapeutic delivery NGLY1, VGF, GAP43 TASP1 4280/4885ENPEP 60/4885GZMB 2119/4885
US-12139744-B2 Stabilisation of biological samples RNASE1, RNASEH1, EWSR1 TASP1 4313/4885ENPEP 1297/4885GZMB 426/4885
US-12240816-B2 Deuterated compounds and uses thereof ALDH1A2, SSB, DBH TASP1 2942/4885ENPEP 389/4885GZMB 2116/4885
US-11007269-B2 P53 degradation inducing molecule and pharmaceutical composition TP53, TP53BP1, MDM2 TASP1 1006/4885ENPEP 566/4885GZMB 1427/4885
US-20250017979-A1 METHODS AND COMPOSITIONS FOR IMPROVING IN VIVO SURVIVAL OF MIDBRAIN DOPAMINE NEURONS CHAT, PINK1, DBH TASP1 1329/4885ENPEP 3281/4885GZMB 1132/4885
US-20250146050-A1 STABILISATION OF BIOLOGICAL SAMPLES RNASE1, RNASEH1, EWSR1 TASP1 4313/4885ENPEP 1297/4885GZMB 426/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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