SCHEMBL27875403

SCHEMBL27875403

O=C(OC(Cl)Cl)C(Cl)(Cl)Cl

nearest known ligand 0.35

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.35
TP53 P04637 1/20 0.35
TSHR P16473 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27671488 0.78 ALDH1A1 (0.32) ALDH1A1TP53TSHR
SCHEMBL986627 0.78 ALDH1A1 (0.32) ALDH1A1TP53TSHR
SCHEMBL1707076 0.74 TSHR (0.46) ALDH1A1TP53TSHR
SCHEMBL10412379 0.74 ALDH1A1 (0.33) ALDH1A1TP53TSHR
SCHEMBL1738945 0.74
SCHEMBL10938404 0.72
SCHEMBL6382664 0.72 LMNA (0.31)
SCHEMBL783984 0.71 THRB (0.42)
SCHEMBL10603804 0.70 ALDH1A1 (0.30) ALDH1A1TP53TSHR
SCHEMBL784612 0.70 L3MBTL1 (0.31) ALDH1A1TP53TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114686481-B Interference RNA for inhibiting CFD expression and preparation method and application thereof 北京键凯科技股份有限公司 2023-08-15 CN claimed
CN-106008136-A Preparation method of 6,6,12,12-tetramethyl-6,12-dihydroindeno[1,2-b] fluorene 李金铃 2016-10-12 CN claimed
CN-104628805-B A kind of preparation method of amphipathic fat nucleic acid 中国石油大学(华东) 2016-06-08 CN claimed
CN-113929724-B Nucleoside compound, pharmaceutical composition and application thereof 周雨恬 2024-05-31 CN disclosed
CN-111996193-B siRNA sequence for effectively inhibiting expression of epidermal growth factor receptor 北京键凯科技股份有限公司 2024-02-20 CN disclosed
CN-109957566-B Modified oligonucleotides and compounds useful for synthesizing modified oligonucleotides 广州市锐博生物科技有限公司 2023-08-25 CN disclosed
CN-114686481-B Interference RNA for inhibiting CFD expression and preparation method and application thereof 北京键凯科技股份有限公司 2023-08-15 CN disclosed
CN-116139289-A SiRNA drug targeting hepatic stellate cells and preparation method and application thereof 南京农业大学 2023-05-23 CN disclosed
CN-116144661-A Interference RNA for inhibiting hsa_circ_0000825 gene expression and application thereof 南京邮电大学 2023-05-23 CN disclosed
CN-109957565-B Modified siRNA molecule and application thereof 广州市锐博生物科技有限公司 2023-04-07 CN disclosed
CN-115747216-A Interfering RNA for inhibiting expression of complement factor C3 and application thereof 北京键凯科技股份有限公司 2023-03-07 CN disclosed
CN-102933557-B Radiation protection immunomodulator compounds and method 彼得·麦卡勒姆癌症研究所 2016-08-03 CN disclosed
CN-104628805-B A kind of preparation method of amphipathic fat nucleic acid 中国石油大学(华东) 2016-06-08 CN disclosed
CN-102512667-B Lipid complex of a kind of insulin and preparation method thereof and preparation INSTITUTE OF MATARIA MEDICA, CHINESE ACADEMY OF MEDICAL SCIENCES (CN) 2015-08-19 CN disclosed
CN-102573889-B Lipid complex of insulin, preparation method and preparation thereof INSTITUTE OF MATARIA MEDICA, CHINESE ACADEMY OF MEDICAL SCIENCES (CN) 2014-10-22 CN disclosed
CN-104001159-A Insulin lipid compound, and preparation method and preparation thereof INST MATERIA MEDICA CAMS 2014-08-27 CN disclosed
CN-102520148-B Method for preparing plane biological/chemical sensing device with convex pattern microarray UNIV SOUTHEAST 2014-01-01 CN disclosed
CN-102520151-A Method for producing quasi three dimensional biological chip UNIV SOUTHEAST 2012-06-27 CN disclosed
CN-102520148-A Method for preparing plane biological/chemical sensing device with convex pattern microarray UNIV SOUTHEAST 2012-06-27 CN disclosed
CN-102512667-A Lipid composition of insulin, preparation method thereof, and preparation thereof INST MATERIA MEDICA CAMS 2012-06-27 CN disclosed