Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.71 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.63 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28038078 | 0.85 | HTT (0.97) | HTTSMN1; SMN2ALDH1A1POLBPKM | |
| SCHEMBL19442012 | 0.81 | KDM4E (0.50) | HTTKDM4ESMN1; SMN2ALDH1A1POLB | |
| SCHEMBL11980693 | 0.81 | TDP1 (0.57) | HTTKDM4ESMN1; SMN2ALDH1A1THRB | |
| SCHEMBL27876376 | 0.79 | HTT (0.80) | HTTKDM4ESMN1; SMN2ALDH1A1POLB | |
| SCHEMBL27876284 | 0.77 | ALDH1A1 (1.00) | HTTSMN1; SMN2ALDH1A1POLBPKM | |
| SCHEMBL992344 | 0.73 | KMT2A (0.47) | HTTKDM4ESMN1; SMN2ALDH1A1POLB | |
| SCHEMBL28069211 | 0.72 | KMT2A (0.60) | HTTKDM4EALDH1A1POLBLMNA | |
| SCHEMBL13636153 | 0.70 | SIGMAR1 (0.65) | KDM4ESMN1; SMN2ALDH1A1POLB | |
| SCHEMBL4384069 | 0.68 | ALDH1A1 (0.71) | KDM4EALDH1A1POLB | |
| SCHEMBL4378521 | 0.68 | KDM4E (0.71) | KDM4ESMN1; SMN2ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102482249-A | TOFA analogs for treating skin disorders or conditions | VALOCOR THERAPEUTICS INC | 2012-05-30 | — | — | CN | claimed |
| CN-102482249-A | TOFA analogs for treating skin disorders or conditions | VALOCOR THERAPEUTICS INC | 2012-05-30 | — | — | CN | disclosed |