SCHEMBL2787901

SCHEMBL2787901

CC(C)COc1ccc(Sc2cccs2)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.40
LMNA P02545 4/20 0.40
HPGD P15428 4/20 0.40
NPC1 O15118 4/20 0.40
RAB9A P51151 2/20 0.40
KDM4E B2RXH2 2/20 0.40
ALDH1A1 P00352 2/20 0.40
HSD17B10 Q99714 2/20 0.40
TP53 P04637 2/20 0.40
TSHR P16473 1/20 0.40
THRB P10828 1/20 0.40
POLB P06746 2/20 0.39
XBP1 P17861 1/20 0.39
SMN1; SMN2 Q16637 4/20 0.38
GPR88 Q9GZN0 1/20 0.38
S1PR1 P21453 1/20 0.37
KMT2A Q03164 3/20 0.37
MEN1 O00255 2/20 0.37
ALOX12 P18054 1/20 0.37
FBP1 P09467 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2784678 0.83 RAB9A (0.48) MAPTHPGDNPC1RAB9AKDM4E
SCHEMBL2786028 0.80 ALDH1A1 (0.49) MAPTLMNAHPGDNPC1RAB9A
SCHEMBL2785886 0.80 RAB9A (0.46) MAPTLMNAHPGDNPC1RAB9A
SCHEMBL2787935 0.80 HPGD (0.42) LMNAHPGDRAB9AALDH1A1TP53
SCHEMBL2787396 0.77 FBP1 (0.43) MAPTHPGDNPC1RAB9AKDM4E
SCHEMBL2786345 0.76 SLC6A4 (0.44) LMNAALDH1A1TSHRFBP1CYP2C9
SCHEMBL2785957 0.75 FBP1 (0.35) MAPTTP53THRBFBP1
SCHEMBL2786171 0.74 FBP1 (0.43) MAPTLMNAHPGDNPC1RAB9A
SCHEMBL123415 0.72 MAPT (0.55) MAPTLMNAHPGDNPC1RAB9A
SCHEMBL23182681 0.71 MAPT (0.45) MAPTLMNAHPGDNPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2218715-B1 PHOTOACID GENERATOR AND PHOTOREACTIVE COMPOSITION SUMITOMO SEIKA CHEMICALS (JP) 2017-06-28 EP disclosed
US-8216768-B2 Photoacid generator and photoreactive composition SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) 2012-07-10 US disclosed
US-20100233621-A1 PHOTOACID GENERATOR AND PHOTOREACTIVE COMPOSITION SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) 2010-09-16 US disclosed
EP-2218715-A1 PHOTOACID GENERATOR AND PHOTOREACTIVE COMPOSITION Sumitomo Seika Chemicals CO. LTD. (JP) 2010-08-18 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100233621-A1 PHOTOACID GENERATOR AND PHOTOREACTIVE COMPOSITION ARSA, SULT1A1, CYBA MAPT 2523/4885LMNA 3630/4885HPGD 1492/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.