Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 15/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | CDC25B | P30305 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27845365 | 0.85 | HCAR3 (0.58) | HCAR3MAPTCDC25BKMT2AMEN1 | |
| SCHEMBL27879476 | 0.85 | HCAR3 (0.66) | HCAR3MAPTKMT2AMEN1 | |
| SCHEMBL27879458 | 0.84 | HCAR3 (0.64) | HCAR3KMT2AMEN1 | |
| SCHEMBL27894392 | 0.80 | HCAR3 (0.54) | HCAR3MAPTKMT2AMEN1 | |
| SCHEMBL27502068 | 0.80 | CASP6 (0.50) | HCAR3KMT2AMEN1 | |
| SCHEMBL27879456 | 0.80 | HCAR3 (0.50) | HCAR3MAPTKMT2A | |
| SCHEMBL27313061 | 0.80 | TSHR (0.58) | HCAR3MAPTKMT2AMEN1 | |
| SCHEMBL27751980 | 0.78 | POLB (0.50) | HCAR3MAPTKMT2AMEN1 | |
| SCHEMBL27700587 | 0.77 | AKR1C3 (0.46) | HCAR3MAPTKMT2A | |
| SCHEMBL10487799 | 0.76 | TSHR (0.52) | HCAR3MAPTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102762101-B | Substituted fused imidazole derivatives, pharmaceutical compositions, and methods of use thereof | HIGH POINT PHARMACEUTICALS LLC | 2014-09-17 | — | — | CN | disclosed |
| CN-103402987-A | 6-Amino-2-phenylamino-1H-benzimidazole-5-carboxamide derivatives and their use as microsomal prostaglandin E2 synthase-1 inhibitors | BOEHRINGER INGELHEIM INT | 2013-11-20 | — | — | CN | disclosed |
| CN-102762101-A | Substituted fused imidazole derivatives, pharmaceutical compositions, and methods of use thereof | HIGH POINT PHARMACEUTICALS LLC | 2012-10-31 | — | — | CN | disclosed |