Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 13/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27879476 | 0.83 | HCAR3 (0.66) | HCAR3MAPTKMT2AALDH1A1 | |
| SCHEMBL27879455 | 0.80 | HCAR3 (0.61) | HCAR3MAPTKMT2A | |
| SCHEMBL27879458 | 0.77 | HCAR3 (0.64) | HCAR3KMT2A | |
| SCHEMBL27502068 | 0.76 | CASP6 (0.50) | HCAR3KMT2A | |
| SCHEMBL4587381 | 0.75 | CASP6 (0.46) | HCAR3ALDH1A1 | |
| SCHEMBL27751980 | 0.73 | POLB (0.50) | HCAR3MAPTKMT2A | |
| SCHEMBL1538816 | 0.72 | LMNA (0.58) | HCAR3MAPTALDH1A1 | |
| SCHEMBL10487799 | 0.72 | TSHR (0.52) | HCAR3MAPTKMT2AALDH1A1 | |
| SCHEMBL27703640 | 0.72 | CASP6 (0.46) | HCAR3 | |
| SCHEMBL27313061 | 0.72 | TSHR (0.58) | HCAR3MAPTKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102762101-A | Substituted fused imidazole derivatives, pharmaceutical compositions, and methods of use thereof | HIGH POINT PHARMACEUTICALS LLC | 2012-10-31 | — | — | CN | disclosed |