Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 16/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | MYC | P01106 | 1/20 | 0.41 |
| ▸ | MAX | P61244 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27879455 | 0.84 | HCAR3 (0.61) | HCAR3KMT2AMEN1 | |
| SCHEMBL27879476 | 0.82 | HCAR3 (0.66) | HCAR3KMT2AMEN1 | |
| SCHEMBL4238591 | 0.78 | HCAR3 (1.00) | HCAR3KMT2AMEN1 | |
| SCHEMBL27502068 | 0.77 | CASP6 (0.50) | HCAR3KMT2AMEN1 | |
| SCHEMBL27879456 | 0.77 | HCAR3 (0.50) | HCAR3KMT2A | |
| SCHEMBL27313061 | 0.76 | TSHR (0.58) | HCAR3KMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL7428031 | 0.74 | HCAR3 (0.76) | HCAR3KMT2AMEN1 | |
| SCHEMBL27751980 | 0.74 | POLB (0.50) | HCAR3KMT2AMEN1 | |
| SCHEMBL27700587 | 0.74 | AKR1C3 (0.46) | HCAR3KMT2A | |
| SCHEMBL1538816 | 0.73 | LMNA (0.58) | HCAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102762101-B | Substituted fused imidazole derivatives, pharmaceutical compositions, and methods of use thereof | HIGH POINT PHARMACEUTICALS LLC | 2014-09-17 | — | — | CN | disclosed |
| CN-102762101-A | Substituted fused imidazole derivatives, pharmaceutical compositions, and methods of use thereof | HIGH POINT PHARMACEUTICALS LLC | 2012-10-31 | — | — | CN | disclosed |