Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 14/20 | 0.66 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | THRB | P10828 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | GFER | P55789 | 1/20 | 0.56 |
| ▸ | PLEC | Q15149 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | CASP6 | P55212 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27879455 | 0.85 | HCAR3 (0.61) | HCAR3MAPTKMT2AMEN1 | |
| SCHEMBL27879456 | 0.83 | HCAR3 (0.50) | HCAR3MAPTALDH1A1KMT2A | |
| SCHEMBL27894389 | 0.83 | ALDH1A1 (0.68) | HCAR3MAPTKDM4EALDH1A1GAA | |
| SCHEMBL27879458 | 0.82 | HCAR3 (0.64) | HCAR3KMT2AMEN1 | |
| SCHEMBL24032 | 0.79 | HCAR3 (1.00) | HCAR3MAPTALDH1A1HTTKMT2A | |
| Hydrochloric Acid SCHEMBL1602524 | 0.78 | HCAR3 (0.97) | HCAR3MAPTALDH1A1HTTKMT2A | |
| SCHEMBL27502068 | 0.78 | CASP6 (0.50) | HCAR3KMT2ACASP6MEN1 | |
| SCHEMBL27313061 | 0.77 | TSHR (0.58) | HCAR3MAPTALDH1A1KMT2ACASP6 | |
| SCHEMBL17938280 | 0.77 | ALDH1A1 (0.68) | HCAR3MAPTKDM4EALDH1A1GAA | |
| SCHEMBL27751980 | 0.75 | POLB (0.50) | HCAR3MAPTKDM4EGAAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102762101-B | Substituted fused imidazole derivatives, pharmaceutical compositions, and methods of use thereof | HIGH POINT PHARMACEUTICALS LLC | 2014-09-17 | — | — | CN | disclosed |
| CN-102762101-A | Substituted fused imidazole derivatives, pharmaceutical compositions, and methods of use thereof | HIGH POINT PHARMACEUTICALS LLC | 2012-10-31 | — | — | CN | disclosed |