Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.61 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | CA1 | P00915 | 1/20 | 0.59 |
| ▸ | CA2 | P00918 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | CA9 | Q16790 | 1/20 | 0.59 |
| ▸ | CASP6 | P55212 | 1/20 | 0.58 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.57 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.57 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.56 |
| ▸ | CYP26B1 | Q9NR63 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5205017 | 0.86 | HDAC1 (0.75) | KMT2AKEAP1MEN1CASP6HDAC1 | |
| SCHEMBL27889027 | 0.86 | ALDH1A1 (0.67) | KMT2AKEAP1MEN1CA1CA2 | |
| SCHEMBL8074277 | 0.85 | ALDH1A1 (0.74) | KMT2AMEN1CA1CA2CA9 | |
| SCHEMBL31681345 | 0.82 | ALDH1A1 (0.63) | CASP6HDAC1HDAC8CYP26A1CYP26B1 | |
| SCHEMBL4616444 | 0.82 | KMT2A (0.66) | KMT2AMEN1HTTCASP6HDAC1 | |
| SCHEMBL11793140 | 0.82 | CA1 (0.85) | KMT2AKEAP1MEN1CA1CA2 | |
| SCHEMBL540915 | 0.82 | CA1 (0.85) | KMT2AKEAP1MEN1CA1CA2 | |
| SCHEMBL5446391 | 0.81 | L3MBTL1 (0.67) | CASP6HDAC1HDAC8CYP26A1CYP26B1 | |
| SCHEMBL11685957 | 0.80 | CA1 (0.61) | KMT2AKEAP1MEN1CA1CA2 | |
| SCHEMBL7122971 | 0.80 | UCHL1 (0.76) | KMT2AKEAP1MEN1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102627624-B | 4-(4-aminobenzene sulfonamide) phenylacetic acid derivative and preparation method and application thereof | UNIV SOUTHWEST | 2014-03-19 | — | — | CN | disclosed |
| CN-102627624-B | 4-(4-aminobenzene sulfonamide) phenylacetic acid derivative and preparation method and application thereof | UNIV SOUTHWEST | 2014-03-19 | — | — | CN | disclosed |
| CN-102627624-A | 4-(4-aminobenzene sulfonamide) phenylacetic acid derivative and preparation method and application thereof | UNIV SOUTHWEST | 2012-08-08 | — | — | CN | disclosed |
| CN-102627624-A | 4-(4-aminobenzene sulfonamide) phenylacetic acid derivative and preparation method and application thereof | UNIV SOUTHWEST | 2012-08-08 | — | — | CN | disclosed |