Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA3 | P22001 | 1/20 | 0.55 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.47 |
| ▸ | DRD2 | P14416 | 5/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | HTR2C | P28335 | 1/20 | 0.47 |
| ▸ | HTR2B | P41595 | 1/20 | 0.47 |
| ▸ | CCR5 | P51681 | 1/20 | 0.45 |
| ▸ | KDM1A | O60341 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | DRD4 | P21917 | 2/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22928915 | 0.85 | KCNA3 (0.66) | KCNA3SIGMAR1DRD2HTR2ACCR5 | |
| SCHEMBL26661831 | 0.84 | SIGMAR1 (0.58) | KCNA3SIGMAR1DRD2CCR5DRD3 | |
| SCHEMBL8257331 | 0.84 | KCNA3 (0.56) | KCNA3SIGMAR1DRD2CCR5DRD3 | |
| SCHEMBL30401098 | 0.83 | KCNA3 (0.55) | KCNA3SIGMAR1DRD2CCR5DRD3 | |
| SCHEMBL14119476 | 0.82 | CKS1B (0.48) | KCNA3SIGMAR1DRD2HTR2AHTR2C | |
| SCHEMBL14119475 | 0.82 | CKS1B (0.48) | KCNA3SIGMAR1DRD2HTR2AHTR2C | |
| SCHEMBL26813618 | 0.80 | SIGMAR1 (0.51) | KCNA3SIGMAR1DRD2CCR5DRD3 | |
| SCHEMBL18845342 | 0.80 | SIGMAR1 (0.57) | KCNA3SIGMAR1DRD2HTR2AHTR2C | |
| SCHEMBL7724067 | 0.79 | KCNA3 (0.59) | KCNA3SIGMAR1DRD2CCR5KMT2A | |
| SCHEMBL7724060 | 0.79 | KCNA3 (0.59) | KCNA3SIGMAR1DRD2CCR5KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102712626-B | Piperazine compounds having PGDS inhibitory effect | TAIHO PHARMACEUTICAL CO LTD | 2014-09-17 | — | — | CN | disclosed |
| CN-102712626-A | Piperazine compounds having PGDS inhibitory effect | TAIHO PHARMACEUTICAL CO LTD | 2012-10-03 | — | — | CN | disclosed |