Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.47 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.47 |
| ▸ | WDR5 | P61964 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | MITF | O75030 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.41 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.41 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.41 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | CRHBP | P24387 | 2/20 | 0.41 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phenyl Biguanide SCHEMBL467623 | 0.88 | ALDH1A1 (0.50) | ALDH1A1SMN1; SMN2RAB9ANPC1MAPT | |
| Phenyl Biguanide SCHEMBL2721730 | 0.86 | ALDH1A1 (0.48) | ALDH1A1SMN1; SMN2RAB9ANPC1MAPT | |
| Phenyl Biguanide SCHEMBL28093786 | 0.86 | ALDH1A1 (0.48) | ALDH1A1SMN1; SMN2RAB9ANPC1MAPT | |
| SCHEMBL3068902 | 0.86 | F2 (0.43) | ALDH1A1RAB9ANPC1MAPTTP53 | |
| Phenyl Biguanide SCHEMBL1989457 | 0.85 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2RAB9ANPC1MAPT | |
| SCHEMBL27846380 | 0.84 | WDR5 (0.54) | TAAR1PTPN1PTPN11WDR5ALDH1A1 | |
| SCHEMBL6157161 | 0.84 | PTPN1 (0.57) | TAAR1PTPN1PTPN11WDR5ALDH1A1 | |
| Phenyl Biguanide SCHEMBL9459112 | 0.83 | ALDH1A1 (0.45) | ALDH1A1SMN1; SMN2RAB9ANPC1MAPT | |
| Phenyl Biguanide SCHEMBL16702225 | 0.83 | GAA (0.48) | ALDH1A1SMN1; SMN2RAB9ANPC1MAPT | |
| Phenyl Biguanide SCHEMBL1592736 | 0.81 | MAPT (0.47) | ALDH1A1SMN1; SMN2RAB9ANPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1606618-B | Novel alkali protease formed by bacillus gibsonii (DSM 14393) and washing and cleaning agents containing said novel alkali protease | HENKEL KGAA | 2013-03-13 | — | — | CN | disclosed |