Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 3/20 | 0.34 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.32 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27896515 | 0.78 | HSD17B10 (0.50) | MAPTALDH1A1KMT2AGAAHSD17B10 | |
| SCHEMBL27896439 | 0.72 | ACKR3 (0.37) | GRM5 | |
| SCHEMBL27896410 | 0.71 | HPGD (0.50) | MAPTALDH1A1KMT2AGAATSHR | |
| SCHEMBL27879644 | 0.71 | GRM5 (0.40) | GRM5 | |
| SCHEMBL27896385 | 0.69 | TSHR (0.48) | ALDH1A1HTTKMT2ATSHR | |
| SCHEMBL27896574 | 0.69 | CHRNB2 (0.40) | ALDH1A1KMT2AGAAPOLB | |
| SCHEMBL27879665 | 0.69 | CHRNA7 (0.51) | ALDH1A1KMT2APKMPOLB | |
| SCHEMBL28054724 | 0.69 | DPP4 (0.43) | KMT2AGAATDP1GRM5POLB | |
| SCHEMBL7408815 | 0.67 | POLB (0.36) | POLB | |
| SCHEMBL27879636 | 0.67 | CHRM2 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102791693-A | Hepatitis c virus inhibitors | BRISTOL MYERS SQUIBB CO | 2012-11-21 | — | — | CN | claimed |