Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | PREP | P48147 | 1/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | MGLL | Q99685 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27896409 | 0.81 | HTT (0.51) | TSHRMEN1KMT2ACYP2C9CYP2C19 | |
| SCHEMBL27896422 | 0.78 | TDP1 (0.42) | MEN1KMT2ACYP2C9CYP2C19KDM4E | |
| SCHEMBL5311265 | 0.76 | MEN1 (0.51) | TSHREPHX2MEN1KMT2ACYP2C9 | |
| SCHEMBL27879605 | 0.76 | SCN9A (0.41) | KMT2AKDM4EPREPHSD11B1ALDH1A1 | |
| SCHEMBL27896407 | 0.76 | HSD11B1 (0.57) | CYP2C9HSD11B1ALDH1A1 | |
| SCHEMBL28054724 | 0.76 | DPP4 (0.43) | EPHX2KMT2AHSD11B1 | |
| SCHEMBL27879632 | 0.75 | EPHX2 (0.50) | EPHX2MEN1KMT2ACYP2C9ALDH1A1 | |
| SCHEMBL1307699 | 0.75 | ALDH1A1 (0.54) | TSHRMEN1KMT2ACYP2C9CYP2C19 | |
| SCHEMBL27896515 | 0.75 | HSD17B10 (0.50) | TSHRMEN1KMT2ACYP2C19ALDH1A1 | |
| SCHEMBL28054630 | 0.74 | HSD17B10 (0.41) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102791693-B | Hepatitis c virus inhibitors | BRISTOL-MYERS SQUIBB CO. (US) | 2016-04-13 | — | — | CN | claimed |
| CN-102791693-A | Hepatitis c virus inhibitors | BRISTOL MYERS SQUIBB CO | 2012-11-21 | — | — | CN | claimed |