Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 4/20 | 0.57 |
| ▸ | GFER | P55789 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.50 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.45 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.45 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.45 |
| ▸ | HTR2A | P28223 | 2/20 | 0.45 |
| ▸ | HTR2C | P28335 | 2/20 | 0.45 |
| ▸ | HTR4 | Q13639 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | HTR1D | P28221 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27896432 | 0.89 | RAB9A (0.52) | HSD11B1GFERRAB9ANR4A2CHRM2 | |
| SCHEMBL27896409 | 0.78 | HTT (0.51) | HSD11B1POLBCYP2C9ALDH1A1 | |
| SCHEMBL27896385 | 0.76 | TSHR (0.48) | HSD11B1CYP2C9ALDH1A1 | |
| SCHEMBL28054630 | 0.74 | HSD17B10 (0.41) | HCRTR1SMN1; SMN2 | |
| SCHEMBL845083 | 0.74 | HSD11B1 (0.53) | HSD11B1GFERPOLBHCRTR1CHRM2 | |
| SCHEMBL13825988 | 0.73 | GFER (0.57) | HSD11B1GFERRAB9APOLBHCRTR1 | |
| SCHEMBL27249755 | 0.73 | HSD11B1 (0.54) | HSD11B1RAB9AHCRTR1CNR1CNR2 | |
| SCHEMBL1952293 | 0.73 | HSD11B1 (1.00) | HSD11B1 | |
| SCHEMBL1952290 | 0.73 | HSD11B1 (1.00) | HSD11B1 | |
| SCHEMBL1952292 | 0.73 | HSD11B1 (1.00) | HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102791693-A | Hepatitis c virus inhibitors | BRISTOL MYERS SQUIBB CO | 2012-11-21 | — | — | CN | claimed |