Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | PDE2A | O00408 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | HCRTR1 | O43613 | 11/20 | 0.39 |
| ▸ | HCRTR2 | O43614 | 10/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.38 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27896539 | 0.78 | ALDH1A1 (0.48) | HSD17B10LMNA | |
| SCHEMBL27896409 | 0.77 | HTT (0.51) | LMNANPSR1HSP90AA1HSP90AB1 | |
| SCHEMBL27896422 | 0.76 | TDP1 (0.42) | PDE2AHCRTR1HCRTR2CYP3A4 | |
| SCHEMBL27879631 | 0.75 | TAS1R3 (0.41) | HSD17B10SMN1; SMN2CYP3A4 | |
| SCHEMBL27896385 | 0.74 | TSHR (0.48) | LMNA | |
| SCHEMBL27896407 | 0.74 | HSD11B1 (0.57) | HCRTR1SMN1; SMN2 | |
| SCHEMBL28054724 | 0.71 | DPP4 (0.43) | — | |
| SCHEMBL27896410 | 0.71 | HPGD (0.50) | LMNASMN1; SMN2 | |
| SCHEMBL27896515 | 0.70 | HSD17B10 (0.50) | HSD17B10LMNAAPOBEC3AAPOBEC3GSMN1; SMN2 | |
| SCHEMBL27879636 | 0.70 | CHRM2 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102791693-B | Hepatitis c virus inhibitors | BRISTOL-MYERS SQUIBB CO. (US) | 2016-04-13 | — | — | CN | claimed |