Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 2/20 | 0.51 |
| ▸ | HTR6 | P50406 | 4/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | PFKFB3 | Q16875 | 2/20 | 0.36 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.36 |
| ▸ | PRKCI | P41743 | 1/20 | 0.36 |
| ▸ | HTR1D | P28221 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | FASN | P49327 | 1/20 | 0.35 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27914433 | 0.87 | CYP2A6 (0.47) | CYP2A6HSD11B1PRKCIFASN | |
| SCHEMBL18029140 | 0.79 | HSD11B1 (0.55) | CYP2A6HTR6HSD11B1HTR1DBRD4 | |
| SCHEMBL18029231 | 0.76 | HTR6 (0.60) | CYP2A6HTR6HSD11B1PFKFB3HTR1D | |
| SCHEMBL6967613 | 0.75 | PRKCI (0.53) | CYP2A6HSD11B1PRKCI | |
| SCHEMBL4944237 | 0.75 | CYP2A6 (0.45) | CYP2A6HTR6L3MBTL1HSD11B1PFKFB3 | |
| SCHEMBL21237213 | 0.75 | FAAH (0.46) | CYP2A6 | |
| SCHEMBL19903845 | 0.74 | HTR1D (0.59) | CYP2A6HTR6HSD11B1HTR1DBRD4 | |
| SCHEMBL4940378 | 0.73 | CYP2A6 (0.44) | CYP2A6HTR6HSD11B1BRD4 | |
| SCHEMBL18029368 | 0.72 | HTR7 (0.49) | CYP2A6L3MBTL1PRKCI | |
| SCHEMBL506374 | 0.72 | CYP2A6 (0.49) | CYP2A6L3MBTL1PRKCI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103003233-A | Novel hydroxamic acid derivative | TAISHO PHARMACEUTICAL CO LTD | 2013-03-27 | — | — | CN | disclosed |