Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRPF1 | P55201 | 2/20 | 0.53 |
| ▸ | PRKCI | P41743 | 1/20 | 0.47 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.39 |
| ▸ | AURKA | O14965 | 1/20 | 0.39 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.39 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.39 |
| ▸ | GSK3A | P49840 | 1/20 | 0.39 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.39 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.39 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.39 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3481207 | 0.75 | BRPF1 (0.62) | BRPF1PRKCIALDH1A1MAPTKDM4E | |
| SCHEMBL30193576 | 0.75 | KMT2A (0.50) | BRPF1ALDH1A1MAPTKDM4EL3MBTL1 | |
| SCHEMBL4912683 | 0.75 | KMT2A (0.50) | BRPF1ALDH1A1MAPTKDM4EL3MBTL1 | |
| SCHEMBL31036167 | 0.75 | BRPF1 (0.62) | BRPF1PRKCIALDH1A1MAPTKDM4E | |
| SCHEMBL6263704 | 0.74 | BRPF1 (0.42) | BRPF1 | |
| Hydrochloric Acid SCHEMBL27614396 | 0.73 | BRPF1 (0.61) | BRPF1PRKCIALDH1A1MAPTKDM4E | |
| SCHEMBL28281962 | 0.73 | BRPF1 (0.56) | BRPF1PRKCICHEK1AURKADAPK3 | |
| SCHEMBL3061254 | 0.71 | L3MBTL1 (0.70) | BRPF1PRKCICHEK1AURKADAPK3 | |
| SCHEMBL1465796 | 0.70 | BRPF1 (0.53) | BRPF1PRKCICHEK1AURKADAPK3 | |
| Dimethylamine SCHEMBL11499079 | 0.70 | KMT2A (0.46) | BRPF1ALDH1A1MAPTKDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102781914-B | Indole derivatives | TAKEDA PHARMACEUTICAL | 2014-09-17 | — | — | CN | disclosed |
| CN-102781914-A | Indole derivatives | TAKEDA PHARMACEUTICAL | 2012-11-14 | — | — | CN | disclosed |