Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRPF1 | P55201 | 14/20 | 0.42 |
| ▸ | BRD1 | O95696 | 9/20 | 0.42 |
| ▸ | BRPF3 | Q9ULD4 | 8/20 | 0.42 |
| ▸ | BRD9 | Q9H8M2 | 6/20 | 0.42 |
| ▸ | BRD4 | O60885 | 4/20 | 0.42 |
| ▸ | BRD7 | Q9NPI1 | 2/20 | 0.42 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.42 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.40 |
| ▸ | CDC7 | O00311 | 1/20 | 0.40 |
| ▸ | HTR6 | P50406 | 1/20 | 0.37 |
| ▸ | HPGDS | O60760 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10053515 | 0.77 | BRPF1 (0.45) | BRPF1BRD1BRPF3BRD9BRD4 | |
| SCHEMBL11688507 | 0.76 | MAOA (0.53) | HPGDS | |
| SCHEMBL28265765 | 0.76 | ENPP3 (0.42) | BRPF1BRD1BRPF3BRD9BRD4 | |
| SCHEMBL27969722 | 0.76 | ENPP3 (0.42) | BRPF1BRD1BRPF3BRD9BRD4 | |
| SCHEMBL9226534 | 0.74 | L3MBTL1 (0.65) | BRPF1BRD1BRPF3BRD9BRD4 | |
| SCHEMBL27896908 | 0.74 | BRPF1 (0.53) | BRPF1 | |
| SCHEMBL10022422 | 0.73 | BRPF1 (0.43) | BRPF1BRD1BRPF3BRD9BRD4 | |
| SCHEMBL1338266 | 0.73 | CDC7 (0.40) | BRPF1BRD1BRPF3BRD9BRD4 | |
| SCHEMBL10066950 | 0.73 | CYP2A6 (0.44) | BRPF1BRD1BRPF3BRD9BRD4 | |
| SCHEMBL1113031 | 0.72 | XDH (0.41) | BRPF1BRD1BRPF3BRD9BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1537119-A1 | ANTIDEPRESSANT AZAHETEROCYCLYLMETHYL DERIVATIVES OF HETEROCYCLE-FUSED BENZODIOXANS | Wyeth (US) | 2005-06-08 | — | — | EP | disclosed |
| WO-2004024730-A1 | ANTIDEPRESSANT AZAHETEROCYCLYLMETHYL DERIVATIVES OF HETEROCYCLE-FUSED BENZODIOXANS | WYETH (US) | 2004-03-25 | — | — | WO | disclosed |