Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 4/20 | 0.47 |
| ▸ | CREBBP | Q92793 | 4/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.41 |
| ▸ | LTB4R | Q15722 | 5/20 | 0.39 |
| ▸ | LTB4R2 | Q9NPC1 | 5/20 | 0.39 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | IGLV6-57 | P01721 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27915937 | 0.81 | CREBBP (0.46) | CREBBPKCNQ2S1PR5S1PR1 | |
| SCHEMBL27898283 | 0.80 | BRD4 (0.44) | BRD4CREBBPFFAR1KCNQ2ALOX5 | |
| SCHEMBL27898279 | 0.78 | S1PR1 (0.43) | FFAR1S1PR5S1PR1 | |
| SCHEMBL6348036 | 0.74 | HSPA1A (0.45) | KCNQ2 | |
| SCHEMBL22368680 | 0.67 | CREBBP (0.63) | BRD4CREBBPFFAR1LTB4RLTB4R2 | |
| SCHEMBL29035350 | 0.65 | LTB4R (0.55) | FFAR1LTB4RLTB4R2 | |
| SCHEMBL29523710 | 0.65 | LTB4R (0.55) | FFAR1LTB4RLTB4R2 | |
| SCHEMBL29523427 | 0.65 | LTB4R (0.55) | FFAR1LTB4RLTB4R2 | |
| SCHEMBL28566657 | 0.65 | CREBBP (0.62) | BRD4CREBBPFFAR1LTB4RLTB4R2 | |
| SCHEMBL17673118 | 0.64 | CREBBP (1.00) | BRD4CREBBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103044310-A | Indoline-3-acetic acid derivative and preparation method thereof as well as application of derivative in medicine | UNIV GUIYANG MEDICAL | 2013-04-17 | — | — | CN | disclosed |