Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 3/20 | 0.31 |
| ▸ | CA1 | P00915 | 3/20 | 0.31 |
| ▸ | CA2 | P00918 | 3/20 | 0.31 |
| ▸ | CA7 | P43166 | 3/20 | 0.31 |
| ▸ | CA9 | Q16790 | 3/20 | 0.31 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16128812 | 0.81 | TSHR (0.37) | TSHRLMNAADRA1APDE4DHCAR2 | |
| SCHEMBL16045520 | 0.81 | TSHR (0.46) | TSHRLMNAADRA1APDE4DHCAR2 | |
| SCHEMBL16046615 | 0.81 | TSHR (0.46) | TSHRLMNAADRA1APDE4DHCAR2 | |
| SCHEMBL1088188 | 0.80 | CES2 (0.50) | TSHRLMNAADRA1APDE4DHCAR2 | |
| SCHEMBL9457583 | 0.80 | MAPT (0.34) | TSHRLMNASMN1; SMN2 | |
| SCHEMBL28335562 | 0.79 | TSHR (0.43) | TSHRLMNAADRA1APDE4DHCAR2 | |
| SCHEMBL16046806 | 0.77 | TSHR (0.42) | TSHRLMNAADRA1APDE4DHCAR2 | |
| SCHEMBL1089594 | 0.77 | CA2 (0.44) | TSHRLMNAADRA1APDE4DHCAR2 | |
| SCHEMBL1242991 | 0.77 | TSHR (0.42) | TSHRLMNAADRA1APDE4DHCAR2 | |
| SCHEMBL4521664 | 0.77 | TSHR (0.42) | TSHRLMNAADRA1APDE4DHCAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023197017-A1 | ENANTIOSELECTIVE METHODS FOR PREPARING CHIRAL AMINE INTERMEDIATES | UNIVERSITY OF THE WITWATERSRAND, JOHANNESBURG (ZA) | 2023-10-12 | — | — | WO | claimed |
| US-20250215465-A1 | ENANTIOSELECTIVE METHODS FOR PREPARING CHIRAL AMINE INTERMEDIATES | UNIVERSITY OF THE WITWATERSRAND, JOHANNESBURG (ZA) | 2025-07-03 | — | — | US | disclosed |
| EP-4493708-A1 | ENANTIOSELECTIVE METHODS FOR PREPARING CHIRAL AMINE INTERMEDIATES | University of the Witwatersrand, Johannesburg (ZA) | 2025-01-22 | — | — | EP | disclosed |
| WO-2023197017-A1 | ENANTIOSELECTIVE METHODS FOR PREPARING CHIRAL AMINE INTERMEDIATES | UNIVERSITY OF THE WITWATERSRAND, JOHANNESBURG (ZA) | 2023-10-12 | — | — | WO | disclosed |
| EP-3823774-A1 | SIZING COMPOSITION FOR CASTING MOULDS FOR METAL CASTING, USE THEREOF, AND CASTING MOULDS PROVIDED WITH THE SIZING COMPOSITION | ASK Chemicals GmbH (DE) | 2021-05-26 | — | — | EP | disclosed |
| US-8153839-B2 | Method for synthesis of keto acids or amino acids by hydration of acetylene compound | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2012-04-10 | — | — | US | disclosed |
| US-8133992-B2 | Azepinoindole and pyridoindole derivatives as pharmaceutical agents | EXELIXIS, INC. (US) | 2012-03-13 | — | — | US | disclosed |
| US-20090216044-A1 | METHOD FOR SYNTHESIS OF KETO ACIDS OR AMINO ACIDS BY HYDRATION OF ACETYLENE COMPOUND | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2009-08-27 | — | — | US | disclosed |
| US-7517828-B2 | Chiral broensted acid catalyst for asymmetric synthesis and method of asymmetric synthesis with the catalyst | TOAGOSEI CO., LTD. (JP) | 2009-04-14 | — | — | US | disclosed |
| EP-1932824-A1 | METHOD FOR SYNTHESIS OF KETO ACID OR AMINO ACID BY HYDRATION OF ACETHYLENE COMPOUND | Japan Science and Technology Agency (JP) | 2008-06-18 | — | — | EP | disclosed |
| US-20060276329-A1 | Asymmetric synthesis catalyst based on chiral brsnsted acid and method of asymmetric synthesis with the catalyst | TOAGOSEI CO., LTD. (JP) | 2006-12-07 | — | — | US | disclosed |
| EP-1623971-A1 | ASYMMETRIC-SYNTHESIS CATALYST BASED ON CHIRAL BROENSTED ACID AND METHOD OF ASYMMETRIC SYNTHESIS WITH THE CATALYST | TOAGOSEI CO., LTD. (JP) | 2006-02-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060276329-A1 | Asymmetric synthesis catalyst based on chiral brsnsted acid and method of asymmetric synthesis with the catalyst | LSS, COASY, FASN | TSHR 3114/4885LMNA 1162/4885ADRA1A 2991/4885 |
| US-20090216044-A1 | METHOD FOR SYNTHESIS OF KETO ACIDS OR AMINO ACIDS BY HYDRATION OF ACETYLENE COMPOUND | AADAT, BCAT2, BCAT1 | TSHR 2131/4885LMNA 1229/4885ADRA1A 2450/4885 |
| US-20250215465-A1 | ENANTIOSELECTIVE METHODS FOR PREPARING CHIRAL AMINE INTERMEDIATES | BCAT1, BCAT2, CES1 | TSHR 1369/4885LMNA 1726/4885ADRA1A 616/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.