Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.53 |
| ▸ | P2RX4 | Q99571 | 2/20 | 0.48 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.41 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.41 |
| ▸ | SRC | P12931 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27919443 | 0.86 | PLA2G2A (0.47) | CYP19A1KMT2APLA2G2A | |
| SCHEMBL27919449 | 0.76 | NLRP3 (0.45) | SMN1; SMN2MEN1KMT2AMAPK1KDM4E | |
| SCHEMBL28805704 | 0.73 | ALDH1A1 (0.46) | SMN1; SMN2MEN1KMT2AMAPK1KDM4E | |
| SCHEMBL26477205 | 0.73 | CYP19A1 (0.57) | CYP19A1P2RX4SMN1; SMN2MEN1KMT2A | |
| SCHEMBL17862210 | 0.72 | CYP19A1 (0.70) | CYP19A1P2RX4HDAC3HDAC6 | |
| SCHEMBL29750434 | 0.72 | CYP19A1 (0.70) | CYP19A1P2RX4HDAC3HDAC6 | |
| SCHEMBL22499379 | 0.72 | CYP19A1 (0.56) | CYP19A1P2RX4SMN1; SMN2MEN1KMT2A | |
| SCHEMBL30007452 | 0.72 | CYP19A1 (1.00) | CYP19A1P2RX4SMN1; SMN2MEN1KMT2A | |
| SCHEMBL151053 | 0.72 | CYP19A1 (1.00) | CYP19A1P2RX4SMN1; SMN2MEN1KMT2A | |
| SCHEMBL17112767 | 0.71 | CYP19A1 (0.81) | CYP19A1P2RX4SMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103044313-B | Method for synthesising carbazole compounds | ZHEJIANG UNIVERSITY (CN) | 2014-10-22 | — | — | CN | disclosed |
| CN-103044313-A | Method for synthesising carbazole compounds | UNIV ZHEJIANG | 2013-04-17 | — | — | CN | disclosed |