Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 2/20 | 0.47 |
| ▸ | MAPK8 | P45983 | 6/20 | 0.44 |
| ▸ | TSPO | P30536 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CFTR | P13569 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27901718 | 0.86 | CYP19A1 (0.53) | PLA2G2ACYP19A1KMT2A | |
| SCHEMBL31222301 | 0.77 | CYP19A1 (0.60) | PLA2G2ATSPONPC1CYP19A1LMNA | |
| SCHEMBL2244878 | 0.77 | CYP19A1 (0.60) | PLA2G2ATSPONPC1CYP19A1LMNA | |
| SCHEMBL27919449 | 0.77 | NLRP3 (0.45) | MAPK8LMNAKMT2AHTT | |
| SCHEMBL17969632 | 0.75 | NPC1 (0.51) | PLA2G2ATSPONPC1CYP19A1LMNA | |
| SCHEMBL2246814 | 0.73 | CYP19A1 (0.70) | PLA2G2ATSPONPC1CYP19A1KMT2A | |
| SCHEMBL3855156 | 0.72 | GRIK2 (0.50) | PLA2G2AMAPK8NPC1CYP19A1LMNA | |
| SCHEMBL8173916 | 0.71 | CYP19A1 (0.57) | PLA2G2ATSPONPC1CYP19A1KMT2A | |
| SCHEMBL3854526 | 0.70 | PLA2G2A (0.59) | PLA2G2ANPC1LMNAKMT2APPARG | |
| SCHEMBL6920117 | 0.69 | CA12 (0.48) | PLA2G2AMAPK8TSPONPC1CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103044313-A | Method for synthesising carbazole compounds | UNIV ZHEJIANG | 2013-04-17 | — | — | CN | disclosed |