Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PABPC1 | P11940 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | EEF2K | O00418 | 1/20 | 0.31 |
| ▸ | CCR3 | P51677 | 1/20 | 0.31 |
| ▸ | STING1 | Q86WV6 | 2/20 | 0.31 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.31 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | USP1 | O94782 | 1/20 | 0.30 |
| ▸ | GFER | P55789 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.30 |
| ▸ | BACE1 | P56817 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2790406 | 1.00 | PABPC1 (0.32) | PABPC1CYP2D6ALDH1A1LMNACYP3A4 | |
| SCHEMBL2880505 | 0.95 | STING1 (0.36) | CYP2D6ALDH1A1LMNACYP3A4CYP2C9 | |
| SCHEMBL2880502 | 0.95 | STING1 (0.36) | CYP2D6ALDH1A1LMNACYP3A4CYP2C9 | |
| SCHEMBL2791715 | 0.94 | ALDH1A1 (0.33) | PABPC1CYP2D6ALDH1A1LMNACYP3A4 | |
| SCHEMBL2791712 | 0.94 | ALDH1A1 (0.33) | PABPC1CYP2D6ALDH1A1LMNACYP3A4 | |
| SCHEMBL7900833 | 0.92 | PABPC1 (0.34) | PABPC1CYP2D6ALDH1A1CCR3KLK5 | |
| SCHEMBL2791534 | 0.89 | MMP13 (0.34) | PABPC1CYP2D6ALDH1A1LMNACYP3A4 | |
| SCHEMBL7899253 | 0.89 | PABPC1 (0.32) | PABPC1CYP2D6ALDH1A1LMNACYP3A4 | |
| SCHEMBL2788011 | 0.89 | DPP4 (0.33) | CYP2D6CCR3PIN1ATMUSP1 | |
| SCHEMBL2788008 | 0.89 | DPP4 (0.33) | CYP2D6CCR3PIN1ATMUSP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010111634-A2 | RENIN INHIBITORS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-09-30 | — | — | WO | disclosed |