Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PABPC1 | P11940 | 1/20 | 0.34 |
| ▸ | CMA1 | P23946 | 2/20 | 0.31 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.31 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CCR3 | P51677 | 1/20 | 0.30 |
| ▸ | ACE | P12821 | 1/20 | 0.30 |
| ▸ | CCKAR | P32238 | 2/20 | 0.30 |
| ▸ | CCKBR | P32239 | 2/20 | 0.30 |
| ▸ | HRH2 | P25021 | 1/20 | 0.30 |
| ▸ | HRH1 | P35367 | 1/20 | 0.30 |
| ▸ | IL17A | Q16552 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2790406 | 0.92 | PABPC1 (0.32) | PABPC1KLK5ALDH1A1CYP2D6CCR3 | |
| SCHEMBL2790403 | 0.92 | PABPC1 (0.32) | PABPC1KLK5ALDH1A1CYP2D6CCR3 | |
| SCHEMBL2791715 | 0.90 | ALDH1A1 (0.33) | PABPC1ALDH1A1CYP2D6CCR3 | |
| SCHEMBL2791712 | 0.90 | ALDH1A1 (0.33) | PABPC1ALDH1A1CYP2D6CCR3 | |
| SCHEMBL2880502 | 0.90 | STING1 (0.36) | ALDH1A1CYP2D6 | |
| SCHEMBL2880505 | 0.90 | STING1 (0.36) | ALDH1A1CYP2D6 | |
| SCHEMBL7898847 | 0.90 | MMP13 (0.35) | PABPC1KLK5ALDH1A1KMT2ACYP2D6 | |
| SCHEMBL2791534 | 0.89 | MMP13 (0.34) | PABPC1KLK5ALDH1A1CYP2D6 | |
| SCHEMBL7897783 | 0.89 | PABPC1 (0.33) | PABPC1KLK5PTPN1 | |
| SCHEMBL7901258 | 0.89 | PABPC1 (0.33) | PABPC1KLK5HRH2HRH1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010111634-A2 | RENIN INHIBITORS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-09-30 | — | — | WO | disclosed |