Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STING1 | Q86WV6 | 16/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2880502 | 1.00 | STING1 (0.36) | STING1CYP3A4KDM4EGFERALDH1A1 | |
| SCHEMBL2790406 | 0.95 | PABPC1 (0.32) | STING1CYP3A4GFERALDH1A1LMNA | |
| SCHEMBL2790403 | 0.95 | PABPC1 (0.32) | STING1CYP3A4GFERALDH1A1LMNA | |
| SCHEMBL2791715 | 0.91 | ALDH1A1 (0.33) | CYP3A4GFERALDH1A1LMNACYP2D6 | |
| SCHEMBL2791712 | 0.91 | ALDH1A1 (0.33) | CYP3A4GFERALDH1A1LMNACYP2D6 | |
| SCHEMBL7900833 | 0.90 | PABPC1 (0.34) | ALDH1A1CYP2D6 | |
| SCHEMBL2788172 | 0.89 | STING1 (0.36) | STING1KDM4EGFER | |
| SCHEMBL2788169 | 0.89 | STING1 (0.36) | STING1KDM4EGFER | |
| SCHEMBL2791534 | 0.89 | MMP13 (0.34) | CYP3A4ALDH1A1LMNACYP2D6CYP2C9 | |
| SCHEMBL7898847 | 0.88 | MMP13 (0.35) | CYP3A4ALDH1A1LMNACYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010111634-A2 | RENIN INHIBITORS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-09-30 | — | — | WO | disclosed |
| WO-2010111634-A2 | RENIN INHIBITORS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-09-30 | — | — | WO | disclosed |